Unveiling the Impact of Dynamic Contrast-Enhanced and Diffusion-Weighted MRI in Endometrial and Cervical Carcinoma Management | ||||
| Ain Shams Medical Journal | ||||
| Article 9, Volume 75, Issue 4, December 2024, Page 858-873 PDF (1.15 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/asmj.2024.326282.1324 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Rania Ibrahim  1; ZINAB Metwally2
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| 1Radiodiagnosis, Cairo university, Egypt | ||||
| 2Radiodiagnosis department, hepatic institute. | ||||
| Abstract | ||||
| Background: Cervical and endometrial carcinomas, prevalent among gynecological cancers, often present with symptoms such as irregular vaginal bleeding and are typically diagnosed around the age of 50. The preoperative assessment plays a pivotal role in patient prognosis and survival. Objective: This study aims to assess the effectiveness of diffusion-weighted imaging (DWI) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in preoperative staging and evaluation of endometrial and cervical carcinoma. Methods: In this prospective study, 40 cases of uterine malignancy (20 endometrial carcinomas, 20 cervical carcinomas) were staged using T2WIs, DCE-MRI, and DWI after initial biopsy confirmation. Patients aged 32-76 presented with abnormal vaginal bleeding. The overall staging was correlated with surgical results using the revised FIGO system. Results: In a study of 120 patients with uterine malignancies—60 with endometrial carcinoma and 60 with cervical carcinoma—distinct imaging characteristics were observed. Results indicated an overall accuracy of 75% for T2WIs, 85% for DCE-MRI, and 92.5% for DW-MRI in aligning with surgical staging and FIGO clinical staging. Conclusion: The utilization of dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) enhances the precision of diagnosing and staging cervical and endometrial cancers. This integration improves pre-surgical mapping, treatment response assessment, and outcome prediction. | ||||
| Keywords | ||||
| Cervical tumors; dynamic contrast enhanced MRI; diffusion-weighted MRI; endometrial tumors | ||||
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