Planch leaves
El Souda, S., Mohammed, R., Ibrahim, F., Matloub, A. (2017). Planch leaves. EKB Journal Management System, 16(2), 103-111. doi: 10.4103/epj.epj_10_17
Sahar S.M. El Souda; Reda S. Mohammed; Faten M. Ibrahim; Azza A. Matloub. "Planch leaves". EKB Journal Management System, 16, 2, 2017, 103-111. doi: 10.4103/epj.epj_10_17
El Souda, S., Mohammed, R., Ibrahim, F., Matloub, A. (2017). 'Planch leaves', EKB Journal Management System, 16(2), pp. 103-111. doi: 10.4103/epj.epj_10_17
El Souda, S., Mohammed, R., Ibrahim, F., Matloub, A. Planch leaves. EKB Journal Management System, 2017; 16(2): 103-111. doi: 10.4103/epj.epj_10_17

Planch leaves

Egyptian Pharmaceutical Journal
Volume 16, Issue 2, May 2017, Page 103-111  XML PDF (466.77 K)
DOI: 10.4103/epj.epj_10_17
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Authors
Sahar S.M. El Souda; Reda S. Mohammed; Faten M. Ibrahim; Azza A. Matloub
Abstract
Background and objective

Planch leaves belong to the Sapindaceae family. The study aimed to investigate the phenolic constituents and evaluate the antioxidant and α-amylase inhibitory activities of the plant’s extracts and its major compounds.
Materials and methods
The compounds were isolated through chromatographic techniques from the defatted ethanolic extract (DAEE). Their structures were determined by ultraviolet, mass spectrometer, and nuclear magnetic resonance spectroscopy.
Results
The flavonoids kaempferol 3--(6″galloyl)- apiofuranosyl (1‴→2″)-β-galactopyranoside, kaempferol-3--β-glucopyranosyl(1‴→6″)-β-glucopyranoside, kaempferol 3--(6″galloyl)-apiofuranosyl (1‴→2″)-β-galactopyranoside, rutin, vitexin, isovitexin, orientin, quercetin, kaempferol; the tannins ellagic acid, gallic acid, methyl gallate, 2,6-di--galloyl(α/β)glucoside, 2,3-di--galloyl(α/β)glucoside, and tetragalloyl glucoside in addition to two benzene acetic acid derivatives, harpulliaside A and cavaol B, were isolated from the total bioactive ethanolic extract (TEE). The TEE and the DAEE of have a total phenolic content of 255.5±7.18 and 222.9±6.43 mg gallic acid equivalents/g extract, respectively, and a total flavonoid content of 111.6±3.2 and 102.6±2.6 mg quercetin equivalents/g extract, respectively. With respect to the study, DAEE, TEE, and methyl gallate showed an interesting inhibitory activity on 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) [half maximal inhibitory concentration (IC): 13.3±0.4, 17.7±0.7, and 19.4±0.08 µg/ml, respectively], nitric oxide (IC: 12.8±2.54, 18.3±1.6, and 29.8±1.00 µg/ml, respectively), and α-amylase (IC: 6.1±0.554, 14.4±0.681, and17.5±0.003 µg/ml, respectively).
Conclusion

extracts are rich in phenolic compounds; the aforementioned results suggest that DAEE, TEE, and methyl gallate may be potentially useful in hegemony of obesity and diabetes.
Keywords
antioxidants; α-amylase; cavaol B; Flavonoids; gallic derivatives; harpulliaside A
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