Oral disintegrating tablets | ||||
| Egyptian Pharmaceutical Journal | ||||
| Volume 20, Issue 2, April 2021, Page 105-114 PDF (2.29 MB) | ||||
| DOI: 10.4103/epj.epj_63_20 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Kusuma Anusha; Santosh K. Rada | ||||
| Abstract | ||||
Drug carrier networks are sophisticated because pharmaceutical scientists gain a greater understanding of the performance of biochemical as well as physicochemical parameters. Oral disintegrating tablets (ODTs) are now more commonly available for the treatment of various diseases than other products. Due to its convenience in terms of manufacture and administration, the oral administration route is being studied as the most utilized route. ODTs, particularly for pediatric patients, are considered to be effective drug-delivery systems due to their quick disintegration properties, water-free usage, and ease of swallowing. ‘Orally disintegrating tablets’ are present in solid dosage forms that dissolve in the mouth in less than 60 s without the need for water. Rapid tablet disintegration leads to rapid dissolution and therefore rapid action. ODTs are an ideal treatment for specific populations such as unconscious patients, bedridden patients, dysphagic patients, psychotic patients, geriatric patients, pediatric patients, and young patients with underdeveloped nervous and muscular systems. The main aim of this research paper is to discuss the advantages, drawbacks, formulation problems, manufacturing methods, patented technology, evaluation tests, and marketed formulations of ODTs, their value, different technologies, ideal characteristics, and aspects of formulation and design, future perspectives, and marketed preparations, particularly for pediatric patients. | ||||
| Keywords | ||||
| geriatrics; mass extrusion; orally disintegrating tablets; patient compliance; Pediatrics | ||||
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