Efficacy of nitrous oxide-oxygen inhalation versus oral midazolam-promethazine as sedative agents in pediatric patients | ||
| Egyptian Pharmaceutical Journal | ||
| Volume 21, Issue 4, October 2022, Pages 526-530 PDF (332.41 K) | ||
| DOI: 10.4103/epj.epj_78_22 | ||
| Authors | ||
| Karishma; Sonam Kohli; Mohammed P.K. Rajeesh; Usha Balan; Basanta K. Choudhury; Henston DSouza | ||
| Abstract | ||
| Background Managing difficult and uncooperative pediatric dental patients is a challenging task. Conscious sedation has been propagated as a pharmacological means for handling such situations. Objective To evaluate the effects of sedation using nitrous oxide-oxygen inhalation versus oral midazolam-promethazine in pediatric patients. Patients and methods A total of 100 pediatric patients were selected and divided into two equal categories: group 1 (midazolam-promethazine) and group 2 (NO-O). Ethical committee approval was obtained, and patients were assessed. Data collected were analyzed using an unpaired test. Results Duration of sedation was found to be statistically significant, and a higher duration was found for group 1. No significant differences were noted in the behavior rating scale with either of the combinations and in pulse oximeter readings. Conclusion Midazolam/promethazine is better in inducing longer sedation than NO/O. | ||
| Keywords | ||
| children; conscious sedation; midazolam; nitrous oxide; Oxygen; promethazine | ||
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