An overview of synthetic approaches and the potential bioactivity of different 1,2,3-triazole hybrids
Zaghary, W., Anwar, M., El-Haggar, R., Syam, Y., Hashim, A. (2024). An overview of synthetic approaches and the potential bioactivity of different 1,2,3-triazole hybrids. EKB Journal Management System, 0(), -. doi: 10.4103/epj.epj_112_23
Wafaa A. Zaghary; Manal M. Anwar; Radwan El-Haggar; Yasmin M. Syam; Alaa H. Hashim. "An overview of synthetic approaches and the potential bioactivity of different 1,2,3-triazole hybrids". EKB Journal Management System, 0, , 2024, -. doi: 10.4103/epj.epj_112_23
Zaghary, W., Anwar, M., El-Haggar, R., Syam, Y., Hashim, A. (2024). 'An overview of synthetic approaches and the potential bioactivity of different 1,2,3-triazole hybrids', EKB Journal Management System, 0(), pp. -. doi: 10.4103/epj.epj_112_23
Zaghary, W., Anwar, M., El-Haggar, R., Syam, Y., Hashim, A. An overview of synthetic approaches and the potential bioactivity of different 1,2,3-triazole hybrids. EKB Journal Management System, 2024; 0(): -. doi: 10.4103/epj.epj_112_23

An overview of synthetic approaches and the potential bioactivity of different 1,2,3-triazole hybrids

Egyptian Pharmaceutical Journal
Volume 0, , February 2024    PDF (18.67 M)
DOI: 10.4103/epj.epj_112_23
Authors
Wafaa A. Zaghary; Manal M. Anwar; Radwan El-Haggar; Yasmin M. Syam; Alaa H. Hashim
Abstract
1,2,3-Triazole is considered to be the lead structure for the discovery of many drug molecules. 1,2,3-Triazole has received considerable attention in the field of drug discovery due to its remarkable widespread biological potential. This work summarizes the current synthetic pathways adopted for the synthesis of diverse analogs of 1,2,3-triazole. It also introduces an overview of the latest advances in 1,2,3-triazole hybrid models with various pharmacological activities, their chemical structures, structure–activity relationships, and mechanisms of action.
Keywords
1,2,3-Triazole; metal-catalyzed synthesis; metal-free synthesis; biological activities
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