Synthesis, characterization, and biological activity of silver nanofibers essential oils of prunus dulcis | ||||
| Egyptian Pharmaceutical Journal | ||||
| Volume 0, , February 2024 PDF (3.6 MB) | ||||
| DOI: 10.4103/epj.epj_226_24 | ||||
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| Authors | ||||
| Nuha A.M. Obaid; Noor H. Faisal; Nuha W. Ali; Ruaa G. Ibrahim; Ayat N. Hassan; Ayat J. Kadhum; Ali A.A. Al-Shawi; Mohammed E. Mohmmed; Mohnad Abdalla | ||||
| Abstract | ||||
| Background Prunus dulcis possesses various beneficial qualities, including liver-protective, cardio metabolic, antimicrobial, anti-inflammatory, and anxiety-reducing properties. Furthermore, the oil is a fantastic moisturizing cream for hair and skin, to it can help prevent stretch marks and ultraviolet-visible spectroscopy damage. These biological applications highlight the importance of developing nanotechnology applications for P. dulcis almond oils. Materials and methods In this study, essential oils derived from the fruit of the almond tree (P. dulcis) were employed as reducing agents for producing silver nanofibers (AgNFs). Synthesized AgNFs were characterized using ultraviolet-visible spectroscopy, scanning electron microscopy, and Fourier transform infrared spectroscopy. The biological activities of (AgNFs) were examined. Results The current study showed the absorption of synthesized (AgNFs) at 415 nm. Scanning electron microscopy analysis showed the nanofibers average diameter varied from 200 nm to 10 nm. The biological activities of (AgNFs) were evaluated using minimum inhibitor concentration, half-maximal inhibitory concentration (IC), and flow cytometry tests. The cell cycle test of (AgNFs) showed it arrested with S-phase of two types of human cancer cells (HepG2 liver cancer cells and MDA-MB-231 breast cancer cells). Conclusion These antibacterial and anticancer properties of AgNFs highlight the increased medicinal value of essential oils when coupled with AgNFs produced from almond essential oil. | ||||
| Keywords | ||||
| Antibacterial; Anticancer; Essential oils; Prunus dulcis; silver nanofibers | ||||
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