The Hemogram Parameters in Juvenile Idiopathic Arthritis: Relation to Disease Activity and Ultrasound Findings
Hassan, W., Khashaba, R., Hamed, A., Amer, A. (2025). The Hemogram Parameters in Juvenile Idiopathic Arthritis: Relation to Disease Activity and Ultrasound Findings. EKB Journal Management System, 42(7), 764-774. doi: 10.21608/bmfj.2025.339159.2263
Waleed A. Hassan; Rana A. Khashaba; Asmaa F. Hamed; Arwa S. Amer. "The Hemogram Parameters in Juvenile Idiopathic Arthritis: Relation to Disease Activity and Ultrasound Findings". EKB Journal Management System, 42, 7, 2025, 764-774. doi: 10.21608/bmfj.2025.339159.2263
Hassan, W., Khashaba, R., Hamed, A., Amer, A. (2025). 'The Hemogram Parameters in Juvenile Idiopathic Arthritis: Relation to Disease Activity and Ultrasound Findings', EKB Journal Management System, 42(7), pp. 764-774. doi: 10.21608/bmfj.2025.339159.2263
Hassan, W., Khashaba, R., Hamed, A., Amer, A. The Hemogram Parameters in Juvenile Idiopathic Arthritis: Relation to Disease Activity and Ultrasound Findings. EKB Journal Management System, 2025; 42(7): 764-774. doi: 10.21608/bmfj.2025.339159.2263

The Hemogram Parameters in Juvenile Idiopathic Arthritis: Relation to Disease Activity and Ultrasound Findings

Benha Medical Journal
Article 8, Volume 42, Issue 7, July 2025, Page 764-774  XML PDF (786.76 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2025.339159.2263
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Authors
Waleed A. Hassan1; Rana A. Khashabaorcid 2; Asmaa F. Hamed email orcid 3; Arwa S. Amerorcid 4
1Rheumatology, Rehabilitation and Physical medicine department, Faculty of Medicine, Benha University, Qalyoubia, Egypt
2Clinical and chemical pathology Department, Faculty of Medicine, Benha University, Qalyoubia, Egypt
3Rheumatology, Rehabilitation and Physical medicine department, Faculty of Medicine, Benha University, Qaliobia, Egypt
4Rheumatology, Rehabilitation, and Physical Medicine Department, Faculty of Medicine, Benha University, Qalyoubia, Egypt
Abstract
ABSTRACT
Background: Juvenile idiopathic arthritis (JIA) is an autoimmune chronic disease of childhood with existent challenges to monitoring the disease activity. The hemogram parameters are utilized as inflammatory markers in several diseases. Purpose: This study aimed to evaluate neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), lymphocyte-monocyte ratio (LMR), mean platelet volume (MPV), platelet distribution width (PDW) and red cell distribution width (RDW) in JIA patients with correlating them to disease activity along with ultrasonographic parameters. Subjects and methods: This case-control study incorporated 50 JIA children and 50 healthy control children. Laboratory investigations included the CBC derived parameters (RDW, PDW, MPV, NLR, LMR and PLR), ESR and CRP. Assessment of JIA disease activity was performed. JIA functional status was assessed by Juvenile Arthritis Multidimensional Assessment Report (JAMAR). Musculoskeletal ultrasound (MSUS) was done to JIA children using 10-joint score according to OMERACT definitions. Results: In JIA patients, PDW, MPV and LMR were lower than controls (P
Keywords
Juvenile idiopathic arthritis; Disease activity; Neutrophil-lymphocyte ratio; Platelet-lymphocyte ratio; Musculoskeletal ultrasound
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