Evaluation of S.uric acid in COPD patients | ||
| Benha Medical Journal | ||
| Article 24, Volume 42, Issue 4, April 2025, Pages 608-615 PDF (541.68 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.324288.2210 | ||
| Authors | ||
| Rasha Mohamed Hendy1; Salwa Hassan Mohammed* 2 | ||
| 1benha | ||
| 2Chest department benha university benha faculty of medicine | ||
| Abstract | ||
| Abstract: Airway inflammation and imbalance between oxidant/anti-oxidant mechanisms are postulated to play a major role in the pathogenesis of COPD. The work aimed to evaluate serum uric acid among COPD patients and its correlation with the severity of the disease. Patients and methods: A retrospective cross-sectional study included 50 COPD patients, who attended Benha University Hospital from March 2022 to November 2023. All patients were subjected to the following; written consent from the patient, full history and clinical examination, ABG, CXR (P-A), pulmonary function tests, measuring serum creatinine and urea, measuring serum uric acid by enzymatic colorimetric assay in a fully automated analyzer. Results: There was a highly significant negative correlation between patients’ serum uric acid levels and FEV1.There was a highly significant negative correlation between patients’ serum uric acid levels and FEV1̸ FVC Conclusion: uric acid could be used as a chemical biomarker in predicting COPD severity and staging. Keywords: COPD, uric acid, severity | ||
| Keywords | ||
| COPD; uric acid; severity | ||
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