Evaluation of S.uric acid in COPD patients | ||||
Benha Medical Journal | ||||
Article 24, Volume 42, Issue 4, April 2025, Page 608-615 PDF (541.68 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bmfj.2025.324288.2210 | ||||
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Authors | ||||
Rasha Mohamed Hendy1; Salwa Hassan Mohammed ![]() | ||||
1benha | ||||
2Chest department benha university benha faculty of medicine | ||||
Abstract | ||||
Abstract: Airway inflammation and imbalance between oxidant/anti-oxidant mechanisms are postulated to play a major role in the pathogenesis of COPD. The work aimed to evaluate serum uric acid among COPD patients and its correlation with the severity of the disease. Patients and methods: A retrospective cross-sectional study included 50 COPD patients, who attended Benha University Hospital from March 2022 to November 2023. All patients were subjected to the following; written consent from the patient, full history and clinical examination, ABG, CXR (P-A), pulmonary function tests, measuring serum creatinine and urea, measuring serum uric acid by enzymatic colorimetric assay in a fully automated analyzer. Results: There was a highly significant negative correlation between patients’ serum uric acid levels and FEV1.There was a highly significant negative correlation between patients’ serum uric acid levels and FEV1̸ FVC Conclusion: uric acid could be used as a chemical biomarker in predicting COPD severity and staging. Keywords: COPD, uric acid, severity | ||||
Keywords | ||||
COPD; uric acid; severity | ||||
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