The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency | ||||
Mansoura Journal of Chemistry | ||||
Volume 61, Issue 3, May 2023, Page 52-59 PDF (1.51 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjcc.2023.411556 | ||||
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Authors | ||||
Huda Hamza* 1; Gaber M. Abu El-Reash1; Ahmed M. El-Demeri2 | ||||
1Chemistry Department, Faculty of Science, Mansoura University | ||||
2Oncology and Nuclear Medicine Department, Faculty of Medicine, Mansoura University | ||||
Abstract | ||||
The Co2+ and Ni2+ complexes of H2L ligand were isolated. By using a variety of methods, including elemental (CHN) analysis, FT-IR, UV-visible, and NMR spectroscopy, the assembly of the ligand and its chelates was completely clarified. Additionally, measurements of magnetic field strength and molar conductance were made. Thermal measurements using TG and DTG were made. Horowitz and Coats equations were used to discuss the complex's thermodynamic and kinetic properties. Finally, the compound under test had its biological activity assessed. | ||||
Keywords | ||||
Complexes; TG measurements; kinetic studies; biological activity | ||||
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