The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency
Hamza, H., Abu El-Reash, G., El-Demeri, A. (2023). The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency. EKB Journal Management System, 61(3), 52-59. doi: 10.21608/mjcc.2023.411556
Huda Hamza; Gaber M. Abu El-Reash; Ahmed M. El-Demeri. "The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency". EKB Journal Management System, 61, 3, 2023, 52-59. doi: 10.21608/mjcc.2023.411556
Hamza, H., Abu El-Reash, G., El-Demeri, A. (2023). 'The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency', EKB Journal Management System, 61(3), pp. 52-59. doi: 10.21608/mjcc.2023.411556
Hamza, H., Abu El-Reash, G., El-Demeri, A. The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency. EKB Journal Management System, 2023; 61(3): 52-59. doi: 10.21608/mjcc.2023.411556

The Co2+ and Ni2+ complexes of 2-(2-(2-aminothiazol-4-yl)acetyl)-N-phenylhydrazine-1-carbothioamide ligand and evaluation of their biological potency

Mansoura Journal of Chemistry
Volume 61, Issue 3, May 2023, Pages 52-59    PDF (1.51 M)
Document Type: Original Article
DOI: 10.21608/mjcc.2023.411556
Authors
Huda Hamza* 1; Gaber M. Abu El-Reash1; Ahmed M. El-Demeri2
1Chemistry Department, Faculty of Science, Mansoura University
2Oncology and Nuclear Medicine Department, Faculty of Medicine, Mansoura University
Abstract
The Co2+ and Ni2+ complexes of H2L ligand were isolated. By using a variety of methods, including elemental (CHN) analysis, FT-IR, UV-visible, and NMR spectroscopy, the assembly of the ligand and its chelates was completely clarified. Additionally, measurements of magnetic field strength and molar conductance were made. Thermal measurements using TG and DTG were made. Horowitz and Coats equations were used to discuss the complex's thermodynamic and kinetic properties. Finally, the compound under test had its biological activity assessed.
Keywords
Complexes; TG measurements; kinetic studies; biological activity
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