The Effect of Heart of Palm “Palmetto” on Obese Rats with Induced Diabetic Nephropathy | ||||
| المجلة العلمية للتربية النوعية والعلوم التطبيقية | ||||
| Volume 7, Issue 21, July 2024, Page 163-187 PDF (503.36 K) | ||||
| Document Type: المقالة الأصلية | ||||
| DOI: 10.21608/sjseas.2024.411923 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Ashraf A. Abel Elmeged* 1; Naeem Mohammed Rabeh* 1; Ahmed El-Wahy* 2 | ||||
| 1Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University. | ||||
| 2Graduate student, Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University, Egypt | ||||
| Abstract | ||||
| This study investigated the effects of a high-fat diet with varying levels of date palm pith (palmetto) (5%, 10%, and 15%) on rats with induced diabetic nephropathy. Thirty-five rats were divided into five groups (n=7 each): Group 1 was fed a standard diet and served as the negative control; Group 2 consisted of obese rats with diabetic nephropathy fed a high-fat diet, serving as the positive control; Groups 3 to 5, like Group 2, were fed a high-fat diet but with the addition of dried palm date pits at 5%, 10%, and 15%, respectively. Results indicated that adding palmetto at these levels significantly (P<0.05) increased final body weight, feed intake, and body weight gain percentage compared to the positive control group. Additionally, rats treated with palmetto exhibited a significant increase (p<0.05) in insulin concentration, lower glucose levels, and elevated levels of catalase, as well as improvements in liver and kidney functions were also observed. These findings suggest that palmetto may have a therapeutic role in mitigating complications associated with diabetic nephropathy. | ||||
| Keywords | ||||
| palmetto; diabetes; nephropathy; glucose; liver function; kidney function; antioxidant enzymes | ||||
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