Role of malondialdehyde in the development of interstitial cystitis in Egyptian Patients | ||||
Mansoura Journal of Chemistry | ||||
Volume 56, Issue 2, April 2022, Page 17-21 PDF (626.46 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjcc.2022.412103 | ||||
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Authors | ||||
Rokaya A. Elsalamony* 1; Fardous F. El-Senduny1; El Hefnawy AS2; Omali Elkhawaga3 | ||||
1Biochemistry division, Chemistry department, Faculty of Science, Mansoura University. | ||||
2Urology department, Faculty of Medicine, Mansoura University) | ||||
3Chemistry | ||||
Abstract | ||||
Interstitial cystitis is a chronic disease that affects women mostly changing their lifestyle and affecting their ability to live a normal life. It is hard to diagnose as it intersects and comorbid with many diseases so the treatment of that disease is not easy.There are many theories about its pathogenesis ,one of which is oxidative stress. Experts observed anomalies in each subcellular layer of IC/ PBS patients' bladder tissue,some of it could be a result of lipid peroxidation due to high oxidive stress.Lipid peroxidation produces end-products such as malondialdehyde (MDA) which we will estimate to find the possible relationship between lipid peroxidation and IC. | ||||
Keywords | ||||
lipid-peroxidation; interstitial-cystitis; malondialdehyde; bladder | ||||
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