Synthesis and Characterization of New monocationic pyridine-arylthiophene derivatives | ||
| Mansoura Journal of Chemistry | ||
| Volume 47, Issue 1, February 2020, Pages 31-36 PDF (658.7 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjcc.2020.412866 | ||
| Authors | ||
| Mohamed A. Ismail* ; Ghada A. Abdelwahab; Saad Shaban; Wafaa S. Hamama | ||
| Chemistry Department, Faculty of Science, Mansoura University, 35516 Mansoura, Egypt | ||
| Abstract | ||
| Three new monocationic thienylpyridine derivatives 7a-c were prepared through two sequential steps. First step involved the preparation of carbonitrile derivatives 6a-c in good yields via a Suzuki coupling reaction between the bromothienyl derivative 4 and the appropriate phenylboronic acids 5a-c. Second step involved treatment of carbonitrile derivatives 6a-c with lithium bis-trimethylsilylamide, followed by de-protection step and subsequent hydrochloride salt formation. Chemical structures of the newly synthesized thienylpyridines were confirmed based on their spectral data, Infrared FT-IR, 1H-NMR and mass spectrometry. | ||
| Keywords | ||
| Thiophene derivatives; pyridine derivatives; Suzuki reaction; cationic compounds | ||
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