Synthesis of some novel imidazolone analogues utilizing 4-((2-(4-acetanilide)-5-oxooxazol-4(5h)-ylidene)methyl)phenyl benzenesulfonate synthon | ||
Mansoura Journal of Chemistry | ||
Volume 44, Issue 2, May 2020, Pages 26-31 PDF (924.27 K) | ||
Document Type: Original Article | ||
DOI: 10.21608/mjcc.2020.412975 | ||
Authors | ||
Ahmed Mekabaty* 1; A. S. Fouda2; Samar A. I. A. Mohsen2 | ||
1Chemistry Department, Faculty of Science, Mansoura University | ||
2Chemistry Department, Faculty of Science, Mansoura University, El-Gomhoria Street, ET-35516 Mansoura, Egypt | ||
Abstract | ||
A new series of new imidazolones 3-6 have been achieved via the reaction of the readily obtainable 5-oxazolone 2 with 4-aminophenol, ethyl 4-aminobenzoate, 4-aminoacetophenone and 2-aminobenzoic acid as primary aromatic amines in acetic acid including freshly melted sodium acetate. Furthermore, the imidazolone 3 on reaction with ethyl 2-chloroacetate, acetic anhydride, benzoyl chloride or benzenesulfonyl chloride afforded the corresponding imidazolone derivatives 7-10. The newly imidazolone derivatives have been established by spectral data and elemental analysis | ||
Keywords | ||
Oxazolones; imidazolones; 4-aminoacetophenone; 2-aminopyridine; 2-aminothiazole | ||
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