The utility of Fecal Microbiota Transplantation for Feline Hyperesthesia Syndrome | ||
| SVU-International Journal of Veterinary Sciences | ||
| Volume 8, Issue 1 - Serial Number 23, March 2025, Pages 49-55 PDF (1.12 M) | ||
| Document Type: Research article | ||
| DOI: 10.21608/svu.2025.349862.1360 | ||
| Authors | ||
| Kerem Ural* 1; Hasan Erdoğan2; Songül Erdoğan2; Cemalettin Ayvazoğlu3; Cansu Balıkçı4 | ||
| 1Aydın Adnan Menderes University, Faculty of Veterinary Medicine, Department of Internal Medicine, Aydın/TÜRKİYE | ||
| 2Aydin Adnan Menderes University, Faculty of Veterinary Medicine, Department of İnternal Medicine, Işıklı,Aydın/Turkey | ||
| 3Ardahan University, Nihat Delibalta Göle Vocational School, Department of Laboratory and Veterinary Health, Ardahan/TÜRKİYE | ||
| 4Aydın Adnan Menderes University, Faculty of Veterinary Medicine, Department of Intenal Medicine, Aydın/TÜRKİYE | ||
| Abstract | ||
| Feline hyperesthesia syndrome (FHS) is a little-known syndrome characterized by skin texture fluctuations and behavioral disturbances (self-mutilation, excessive vocalization, jumping, running, tail chasing, etc.). Several long-term attacks of neurodermatological findings were evident in 23 cats of various breeds and both sexes. Depending on the respective clinical response, fecal microbiota transplantation (FMT) was used with heterologous origin between 1 and 4 sessions. Considering the frequency of attacks for clinical signs before FMT intervention, the vast majority of cats exhibited daily attacks/excessive grooming of the flank, lumbar or perineal region, lumbar hyperesthesia, vocalization, mutilation, alopecia, and allodynia. However, the disease phenotypes for FHS and the types of accompanying behavioral disorders recorded before and after FMT suggested that FMT was effective. Three different stress factors and environmental conditions were evaluated separately, showing that loud vocalization, struggling, panting, tremors and hyperesthesia decreased dramatically in response to FMT. In general interpretation, FMT was highly effective and no side effects were noticed or detected. The overall clinical response rate after FMT was 86.95%. Among them, 16 (69.56%) cats showed clinical remission, 4 (17.39%) cats showed clinical improvement and three (13.04%) cats had invalid clinical symptoms. | ||
| Keywords | ||
| Behavioral disorders; Microbiome therapy; Neuro-dermatology | ||
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