Selenium oxyanions from harmful environmental pollutants to beneficial selenium nanoparticles | ||
| Archives of Pharmaceutical Sciences Ain Shams University | ||
| Article 1, Volume 9, Issue 1, June 2025, Pages 1-20 PDF (861.27 K) | ||
| Document Type: Review Article | ||
| DOI: 10.21608/aps.2024.326975.1200 | ||
| Authors | ||
| Alaa A. Hamouda* 1; Nooran S. Elleboudy1; Mohammad M. Aboulwafa1, 2; Nadia A. Hassouna1 | ||
| 1Department of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Cairo, 11566, Egypt | ||
| 2Faculty of Pharmacy, King Salman International University, Ras-Sudr, South Sinai, Egypt | ||
| Abstract | ||
| Selenium, in both organic and inorganic forms, is a necessary trace mineral for human nutrition, it is essential for proper function of the immune system and protection against cancer. Cancer, heart problems, infertility, thyroid conditions, and weakened immune systems are linked to insufficient selenium intake shortage. Selenium is distributed into different environmental compartments by natural and anthropogenic activities, and generally discharged in the form of selenate [SeO42−] and selenite [SeO32−], which are both toxic. Physical-chemical and biological treatment processes have been reported to exhibit good treatment efficiencies for Se from aqueous streams. Moreover, the possibility of the biotic transformation of highly soluble and toxic selenite to less toxic elemental selenium nanoparticles using various bacterial strains and their optimization is a promising and eco-friendly way for its removal from the environment. Especially bacterial conversion is considered one of the best conversion methods for the synthesis of nanoparticles because of their quick growth rate, ease of handling, low cost, and high productivity. Also, selenium nanoparticles have generated interest in medicine as a medicinal agent with negligible side effects. In this review, the beneficial conversion of selenium oxyanions to selenium nanoparticles, their application in the medical field, and various parameters of their biological optimization have been fully discussed and elaborated. In this review, the beneficial conversion of selenium oxyanions to selenium nanoparticles, their application in medical field, and various parameters of their biological optimization have been fully discussed and elaborated. | ||
| Keywords | ||
| Selenate; selenite; toxicity; green synthesis; biogenic selenium nanoparticles | ||
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