Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy
Abdalla Othman, A., Attia, Z., Abaza, K., Tawfic, A. (2025). Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy. EKB Journal Management System, 31(7), 2784-2797. doi: 10.21608/zumj.2025.366246.3865
Ali Ibrahim Abdalla Othman; Zainab Mostafa Attia; Kamelia Ahmed Abaza; Ahmed M. Tawfic. "Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy". EKB Journal Management System, 31, 7, 2025, 2784-2797. doi: 10.21608/zumj.2025.366246.3865
Abdalla Othman, A., Attia, Z., Abaza, K., Tawfic, A. (2025). 'Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy', EKB Journal Management System, 31(7), pp. 2784-2797. doi: 10.21608/zumj.2025.366246.3865
Abdalla Othman, A., Attia, Z., Abaza, K., Tawfic, A. Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy. EKB Journal Management System, 2025; 31(7): 2784-2797. doi: 10.21608/zumj.2025.366246.3865

Effect of Intravenous Magnesium Sulphate, Lidocaine or Dexamethasone on Incidence and Severity of Laryngospasm and Postoperative Pain in Pediatrics Undergoing Adenotonsillectomy

Zagazig University Medical Journal
Volume 31, Issue 7, July 2025, Page 2784-2797  XML PDF (1.1 MB)
Document Type: Original Article
DOI: 10.21608/zumj.2025.366246.3865
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Authors
Ali Ibrahim Abdalla Othman email 1; Zainab Mostafa Attia2; Kamelia Ahmed Abaza2; Ahmed M. Tawfic3
1Anesthesia, Intensive Care and Pain Management Department, Faculty of Medicine, Tripoli University, Libya
2Professor of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Egypt
3Lecturer of Anesthesia, Intensive Care and Pain Management, Faculty of Medicine, Zagazig University, Egypt
Abstract
Background: Post-extubation laryngospasm is a common and serious complication in Pediatrics Undergoing Adenotonsillectomy. This study aimed to evaluate and compare the effect of intravenous magnesium sulphate, lidocaine or dexamethasone on the incidence and severity of laryngospasm and postoperative pain in pediatrics undergoing adenotonsillectomy. Methods: Included Seventy-Five children undergoing adenotonsillectomy were divided into three groups, each of 25 children. Group M; received an intravenous infusion of 15mg/kg 10% magnesium sulfate in 50ml of 0.9% sodium chloride over 10min. Group L; received an intravenous infusion of 1 mg/kg 2% lidocaine in 50ml of 0.9% sodium chloride over 10min. Group D; received an intravenous infusion dexamethasone 0.5mg/kg in 50ml of 0.9% sodium chloride over 10min. Results: There was a significant difference among the studied groups regarding recovery time that was higher in group I than group II and III. None of patients any complications, regarding incidence of laryngospasm after extubation at 1, 5, 10 and 15 minutes, which had no statistically significant differences. Conclusion: that intravenous magnesium sulfate is more effective than intravenous lidocaine and dexamethasone in reducing the incidence and severity of laryngospasm, however, it is associated with a relatively prolonged recovery time compared with lidocaine and dexamethasone.
Keywords
Laryngospasm; Adenotonsillectomy; Magnesium sulfate; Lidocaine; Dexamethasone
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