Histopathological Study of Warts in Egyptian Patients | ||
| The Egyptian Journal of Hospital Medicine | ||
| Article 181, Volume 98, Issue 1, January 2025, Pages 1289-1293 PDF (678.72 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/ejhm.2025.418847 | ||
| Abstract | ||
| Background: Cutaneous warts are regarded as the primary manifestation of human papillomavirus (HPV) types. The cell-mediated immune response is believed to be essential for the clearance of HPV. Aim: To study histopathological changes in warts of Egyptian. Patients and Methods: The research involved 25 cases with warts. Histopathologic ally, Skin specimens from lesions have been collected, fixed, sectioned, and stained with H&E for examination under light microscopy and subsequent photography. Results: Biopsies demonstrated variable degrees of papillomatosis, hyperkeratosis, and acanthosis. Also, perinuclear space (koilocyte) and pyknotic nucleus have been discovered. They also showed that most of the patients (56%) have grade 3 hyperkeratosis and parakeratosis while 64% of the patients have grade 2 acanthosis. It also showed that most of the patients (44%) have grade 3 papillomatosis, while 55% of the patients have grade 0 dermal infiltrate. Conclusion: It was concluded that HPV caused mainly the same histopathological changes with different grades. | ||
| Keywords | ||
| Cutaneous warts; Histopathological; Biopsies | ||
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