Microfragmented Adipose Tissue Injection Compared to Hyaluronic Acid for Treatment of Temporomandibular Joint Osteoarthritis. (A Randomized Clinical Trail) | ||||
| Egyptian Dental Journal | ||||
| Volume 71, Issue 2, April 2025, Page 1243-1250 PDF (1.09 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2025.356964.3365 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
nahla mahmoud awadallah   1; mutaz al khair alsayed 2; hesham Alsayed eLhawary. 3
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| 1Lecturer at Oral and Maxillofacial Department Faculty of Dentistry, Cairo University | ||||
| 2Professor, Oral and Maxillofacial Surgery, Faculty of Dentistry, Cairo University. | ||||
| 3Msc Student, Oral and Maxillofacial Department, Faculty of Dentistry, Cairo University | ||||
| Abstract | ||||
| Abstract: Objective: This study aimed to evaluate the effectiveness of standard hyaluronic acid (HA) injections following arthrocentesis compared to micro-fragmented adipose tissue injection derived from the buccal fat pad. Methods: 26 patients with temporomandibular joint disorders were randomly assigned to two groups: Group A; which received HA injections, and Group B; which received adipose tissue injections. Pain levels were assessed using the visual analog scale, and function was measured by maximum interincisal opening at five intervals: before the procedure, after day one, 1 week, 1 month, and finally after 3 months post-procedure. Results: Both groups exhibited significant improvements and positive effects on pain relief, quality of life, and functional mouth opening compared to their baseline measurements. Conclusion: Initial and final results suggest that micro-fragmented adipose tissue injections may offer enhanced benefits in terms of pain reduction, improved life quality, and functional improvement compared to the conventional Hyaluronic acid (HA) treatment. | ||||
| Keywords | ||||
| TMJ disorders; Adipose- tissue injection; pain relief | ||||
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