Isolation and Identification of Multi-Drug-Resistant Bacteria from the Skin of Diabetic Patients in Mosul, Iraq
Ahmed, O., Al-hashimi, H., Alhealy, N., Altaii, H., Saadi, A. (2025). Isolation and Identification of Multi-Drug-Resistant Bacteria from the Skin of Diabetic Patients in Mosul, Iraq. EKB Journal Management System, 11(1), 293-302. doi: 10.21608/jbaar.2025.350760.1136
Omaema Nawfal Ahmed; Hadeel Tahseen Al-hashimi; Noor Ahmed Shehab Alhealy; Hiyam Adil Altaii; Ali M Saadi. "Isolation and Identification of Multi-Drug-Resistant Bacteria from the Skin of Diabetic Patients in Mosul, Iraq". EKB Journal Management System, 11, 1, 2025, 293-302. doi: 10.21608/jbaar.2025.350760.1136
Ahmed, O., Al-hashimi, H., Alhealy, N., Altaii, H., Saadi, A. (2025). 'Isolation and Identification of Multi-Drug-Resistant Bacteria from the Skin of Diabetic Patients in Mosul, Iraq', EKB Journal Management System, 11(1), pp. 293-302. doi: 10.21608/jbaar.2025.350760.1136
Ahmed, O., Al-hashimi, H., Alhealy, N., Altaii, H., Saadi, A. Isolation and Identification of Multi-Drug-Resistant Bacteria from the Skin of Diabetic Patients in Mosul, Iraq. EKB Journal Management System, 2025; 11(1): 293-302. doi: 10.21608/jbaar.2025.350760.1136

Isolation and Identification of Multi-Drug-Resistant Bacteria from the Skin of Diabetic Patients in Mosul, Iraq

Journal of Bioscience and Applied Research
Volume 11, Issue 1, March 2025, Page 293-302  XML PDF (801.51 K)
Document Type: Original Article
DOI: 10.21608/jbaar.2025.350760.1136
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Authors
Omaema Nawfal Ahmed1; Hadeel Tahseen Al-hashimi2; Noor Ahmed Shehab Alhealy3; Hiyam Adil Altaii4; Ali M Saadi email 5
1Department of Anesthesia Techniques, Mosul Medical Technical Institute, Northern Technical University, Iraq
2Department of Medical Laboratory Technologies, Mosul Medical Technical Institute, Northern Technical University, Iraq
3Optometry Techniques Department Department / Mosul Medical Technical Institute / Northern Technical University, Mosul, Iraq
4Department of Biology, Faculty of Science, Mosul University, Mosul, Iraq
5Department of Medicinal Plant Technologies, Technical Agricultural College, Northern Technical University, Iraq
Abstract
Gramme-positive bacteria were shown to be the primary cause of skin infections associated with diabetes, and they showed varying degrees of resistance to most antibiotics. Additionally, Vancomycin-resistant bacterial isolates were inhibited when a chloromazine minimal inhibitory concentration was employed in conjunction with vancomycin. Methodology and results: The current study isolated and identified the bacteria that cause skin infections in diabetic patients. Among the 20 swabs from the skin of diabetic patients, 11(55%) isolates grew and fermented the mannitol salt agar, 7(35%) of them coagulated the plasma in the coagulase test and were positive to catalase test and produced Beta haemolysis on blood agar. The resistance to antibiotics shows all (100%) isolates resistant to Benzylpenicillin and Oxacillin, 5 (71.5%) of isolates Staphylococcus aureus, resistant to Tetracycline, 4 (57%) isolates resistant to Erythromycin, 6 (85.7%) isolates resistant to Clindamycin, and 1 (14%) of isolates resistant to Fusidic acid, vancomycin, teicoplanin, and rifampicin, respectively.
Conclusion: According to the study, most skin ulcers in diabetic individuals are caused by gram-positive bacteria, which also exhibit multiple drug resistance. The combination of chlorpromazine and vancomycin also inhibited the bacterial resistance to the antibiotic, improving the likelihood that these ulcers could be treated. It is also advised that more research be done to determine how effective this medication is before applying it to human skin.
Keywords
diabetic patients; MDRB; skin inflammation; CPZ; Vitek 2 compact
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