Effect of Long–Term Cigarette Smoking on Certain Hematological Parameters | ||||
| Journal of Bioscience and Applied Research | ||||
| Article 10, Volume 11, Issue 2, June 2025, Page 484-489 PDF (355.81 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jbaar.2025.353707.1141 | ||||
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| Authors | ||||
| Ali S. Moalif1; Mohammed Ali shallan2; Jaafar Hamid Jaafar3; Naser A. Naser4 | ||||
| 1Department of Biology, Al-Mustaqbal University, Babylon, Iraq. | ||||
| 2Dentistry Department, Al-Mustaqbal University, Babylon, Iraq. | ||||
| 3Department of Biology, Al-Mustaqbal University, Babylon, Iraq | ||||
| 4Department of Biochemistry, Al-Musatqbal University, Babylon, Hilla, 51001, Iraq. | ||||
| Abstract | ||||
| Background: Smoking is a major global health concern, playing a significant factor in the initiation and progression of various chronic illnesses such as cardiovascular diseases and lung cancer, among others. The American Cancer Society reports that tobacco-related deaths in the United States surpass those caused by alcohol, motor vehicle accidents, HIV, and illicit drugs combined. Objective of work: To investigate how heavy cigarette smoking affects different blood parameters, including white blood cell (WBC) and red blood cell (RBC) counts, platelet levels, and specific hematological indices like hemoglobin (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC) in male smokers, with comparisons made to non-smokers. Methods: The research included 150 healthy male participants from the Hilla city population, categorized into two groups: 100 smokers and 50 non-smokers (serving as the control group). A 5 ml blood sample was collected from each participant under sterile conditions for complete blood analysis. The data obtained were statistically analyzed and compared between the two groups. Results: The analysis revealed significant differences in several hematological parameters in smokers compared to non-smokers, focusing on WBC, RBC, and platelet counts being significantly higher in smokers (P≤0.05). Additionally, levels of HCT, MCV, and HGB were notably elevated in smokers compared to non-smokers. However, the MCH and MCHC values were slightly higher in smokers than in non-smokers, though these differences were not statistically significant. | ||||
| Keywords | ||||
| smoking; Hematological changes; Blood indices | ||||
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