Efficacy of transverse sinus stenting in fulminant idiopathic intracranial hypertension in patients with high grade papilledema grade 3 and 4 | ||||
| Medicine Updates | ||||
| Articles in Press, Accepted Manuscript, Available Online from 01 April 2025 PDF (1.36 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/muj.2025.368776.1215 | ||||
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| Authors | ||||
Mohamed Abd ELRhman ELassy  1; Ayman Elsayed Galhoum2; Farouk Hassan ELkeden3; Amr Said Abu Elfadle4; Ehab Mahmoud Ghoneim5; Raghda Shawky El-Gendy6; Ahmed Sameh Nada7
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| 1Neurosurgery department, faculty of medicine, portsaid university , portsaid city , Egypt | ||||
| 2Head of neurosurgery department, faculty of medicine, Port-Said university, Port-Said, Egypt. | ||||
| 3MD in Intervention Radiology, Professor of Interventional Radiology, Faculty of Medicine, Cairo University, Cairo, Egypt | ||||
| 4Assistant Professor of Neurosurgery at Neurosurgery Department, Faculty of Medicine, Portsaid University, Port Said, Egypt. | ||||
| 5MD in Ophthalmology, Professor of Ophthalmology, Head of Ophthalmology Department, Faculty of Medicine, Port Said University, Port-Said, Egypt | ||||
| 6MD in Ophthalmology, Department of Ophthalmology, Faculty of Medicine, Port-Said University, Port-Said, Egypt. | ||||
| 7MD in Neurosurgery and Neuro-intervention. Lecturer of neurosurgery, neurosurgery department, Faculty of Medicine, Port Said University, Port Said, Egypt. | ||||
| Abstract | ||||
| Back ground: Idiopathic intracranial hypertension (IIH) is an increase in intracranial pressure without intracranial mass or any known etiology. The major morbidity with IIH is visual loss due to secondary papilledema. Aim of the study: The aim is to evaluate the efficacy of transverse sinus stenting in patients with fulminant IIH due to transverse sinus stenosis (TSS) with high grade papilledema III and IV. Methodology: It is pre followed by post intervention; prospective study was done on 70 patients diagnosed with fulminant IIH due to TSS with high grade papilledema III and IV over 2 years. Diagnostic and therapeutic angiogram with stenting was done at AL-Nasr hospital - one of comprehensive health insurance hospitals in port-said city - and the military hospital. Results: The study evaluates 70 patients; the majority were female (88.6%) with a mean age of 37.88 years and a mean BMI of 33.5 kg/m². Before stenting, most patients had severe headaches (76.7%), blurred vision (56.7%), and tinnitus (100%). After stenting, (50%) had no headaches, (88.3%) had no blurred vision, and tinnitus totally resolved. Before stenting, most patients had grade III (88.7%) or grade IV (11.3%) papilledema. After stenting, (53%) had no papilledema. Stenting reduced mean CSF pressure from 45.82 cmH2O to 19.94 cmH2O and median venous pressure gradient from 10 mmHg to 2 mmHg. Two patients experienced re-stenosis and required re-stenting. Conclusion: Transverse sinus stenting is a safe and effective procedure in treating patients with fulminant IIH due to TSS with high grade papilledema III and IV. | ||||
| Keywords | ||||
| Cerebral venous sinus stenting; Fulminant idiopathic intracranial hypertension; Papilledema and Transverse sinus stenosis | ||||
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