Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan
gabri, M., abd el moneim, H., mohammad, M., Mohsen, M., Zaky, E. (2025). Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan. EKB Journal Management System, (), -. doi: 10.21608/aumj.2025.369461.1213
magda farghali gabri; Hanan Mohammed abd el moneim; mostafa omar mohammad; Mousa Mohsen; Edrees Hasan Zaky. "Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan". EKB Journal Management System, , , 2025, -. doi: 10.21608/aumj.2025.369461.1213
gabri, M., abd el moneim, H., mohammad, M., Mohsen, M., Zaky, E. (2025). 'Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan', EKB Journal Management System, (), pp. -. doi: 10.21608/aumj.2025.369461.1213
gabri, M., abd el moneim, H., mohammad, M., Mohsen, M., Zaky, E. Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan. EKB Journal Management System, 2025; (): -. doi: 10.21608/aumj.2025.369461.1213

Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan

Aswan University Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 06 April 2025  XML
Document Type: Original Article
DOI: 10.21608/aumj.2025.369461.1213
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Authors
magda farghali gabri1; Hanan Mohammed abd el moneim2; mostafa omar mohammad email 3; Mousa Mohsen4; Edrees Hasan Zaky5
1pediatrics, faculty of medicine, Aswan University, Aswan, Egypt.
2Faculty of Medicine, Aswan University, Egypt
3pediatric department, Aswan university, Egypt
4pediatric department, Aswan University, Egypt
5pediatric department, Faculty of Medicine, Assiut University, Egypt
Abstract
Abstract
Background: Clinical studies in adults from developed countries have implicated Helicobacter pylori infections in thrombocytopenia. However, research in children, particularly in underdeveloped countries, remains scarce.
Objectives: To investigate the association between H. pylori infection and platelet indices in pediatric patients.
Methods: This cross-sectional observational study included 195 children with dyspepsia recruited from the gastroenterology pediatric department of Aswan University Hospital.
Results: Children with H. pylori infection had significantly lower hemoglobin levels (11.015 ± 1.109 g/dL vs. 11.553 ± 1.00 g/dL, p=0.015), reduced platelet counts (p=0.004), and higher prevalence of low MCV (64.6% vs. 25.5%, p<0.001), low MCH (20.8% vs. 2.13%, p=0.004), leucopenia (27.1% vs. 8.5%, p=0.018), and low MPV (22.9% vs. 4.3%, p=0.014) compared to H. pylori-negative children.
Conclusion: H. pylori infection is associated with hematological alterations, including lower hemoglobin levels, reduced platelet indices, and altered red cell indices, suggesting its potential role in anemia and nutritional deficiencies.
Key words: H. Pylori, platelets, children
Keywords
Key words: H. Pylori; platelets; children
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