Association Between Helicobacter Pylori Infection and Platelet Indices Among the Pediatric Population in Aswan | ||
| Aswan University Medical Journal | ||
| Article 12, Volume 5, Issue 3, September 2025, Pages 112-117 PDF (469.74 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aumj.2025.369461.1213 | ||
| Authors | ||
| magda farghali gabri1; Hanan Mohammed abd el moneim1; mostafa omar mohammad* 1; Mousa Mohsen1; Edrees Hasan Zaky2 | ||
| 1Department of pediatrics, faculty of medicine, Aswan University | ||
| 2pediatric department, Faculty of Medicine, Assiut University, Egypt | ||
| Abstract | ||
| Abstract Background: Clinical studies in adults from developed countries have implicated Helicobacter pylori infections in thrombocytopenia. However, research in children, particularly in underdeveloped countries, remains scarce. Objectives: To investigate the association between H. pylori infection and platelet indices in pediatric patients. Methods: This cross-sectional observational study included 195 children with dyspepsia recruited from the gastroenterology pediatric department of Aswan University Hospital. Results: Children with H. pylori infection had significantly lower hemoglobin levels (11.015 ± 1.109 g/dL vs. 11.553 ± 1.00 g/dL, p=0.015), reduced platelet counts (p=0.004), and higher prevalence of low MCV (64.6% vs. 25.5%, p<0.001), low MCH (20.8% vs. 2.13%, p=0.004), leucopenia (27.1% vs. 8.5%, p=0.018), and low MPV (22.9% vs. 4.3%, p=0.014) compared to H. pylori-negative children. Conclusion: H. pylori infection is associated with hematological alterations, including lower hemoglobin levels, reduced platelet indices, and altered red cell indices, suggesting its potential role in anemia and nutritional deficiencies. Key words: H. Pylori, platelets, children | ||
| Keywords | ||
| Key words: H. Pylori; platelets; children | ||
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