Alterations in time intervals of ductus venous in growth-restricted fetuses | ||||
| Journal of Recent Advances in Medicine | ||||
| Volume 6, Issue 1, January 2025, Page 9-16 PDF (1.47 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jram.2025.311073.1261 | ||||
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| Authors | ||||
Anhar M. Ismaeil  1; Hanaa A. Yonis2; Alshimaa A. Abdel-latif2
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| 1Obstetrics and Gynecology Department, Al-Galaa Teaching Hospital, Cairo, Egypt. | ||||
| 2Obstetrics and Gynecology Department, Faculty of Medicine for Girls, Cairo, Al-Azhar University, Egypt. | ||||
| Abstract | ||||
| ABSTRACT Background: Small-for-gestational-age (SGA) is a term used to describe an infant whose birth weight is below the 10th centile for the appropriate gestational age. Objective: To screen the time intervals of ductus venosus waveforms in growth-restricted fetuses to predict fetal hypoxia, placental insufficiency and adverse outcome at delivery time to improve the perinatal outcome. Methodology: This case control study involved fifty individuals with singleton pregnancies at 28-32 weeks’ gestational age complicated by intrauterine growth retardation (IUGR), contrasted with a control group of 50 age-matched women, performed at Al-Zahraa Hospital, Al-Azhar University, over one year from January 2021 to December 2021. Results: The mean systolic velocity (SDV) interval in IUGR group and control group was 275.27 ±26.69 and 271.13 ±31.17 respectively. The mean diastolic ductus venosus (DDV) interval was 221.87 ±25.00 in IUGR group and 135.26 ±40.65 in control group. DDV interval showed a statistically significant increase in IUGR group contrasted with the control group. DDV interval can significantly determine IUGR at a cutoff 197.85 and AUC was 0.975 with high sensitivity, high specificity, positive predictive value (PPV) and negative predictive value (NPV) were 94%, 100%, 100% and 94.3% consequently (p<0.001). Meanwhile, SDV interval can insignificantly determine IUGR at cutoff 245.98 and AUC was 0.544 with sensitivity, specificity, PPV & NPV was 84%, 32%, 55% & 66.7% consequently (p>0.05). Conclusion: The study suggested that the screening of ductus venosus waveforms in growth-restricted fetuses can predict fetal hypoxia, placental insufficiency, and adverse outcomes, potentially improving perinatal outcomes. | ||||
| Keywords | ||||
| SGA; small-for-gestational-age, ductus venous; fetuses, IUGR | ||||
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