Synthesis of new imidazolone derivatives and evaluated their biological activities
Mostafa, W., Donia, S., El-gazzar, A. (2018). Synthesis of new imidazolone derivatives and evaluated their biological activities. EKB Journal Management System, 5(4), 349-371. doi: 10.21608/jbes.2018.421573
Wesam A. Mostafa; Shafey G. Donia; Amaal Y. El-gazzar. "Synthesis of new imidazolone derivatives and evaluated their biological activities". EKB Journal Management System, 5, 4, 2018, 349-371. doi: 10.21608/jbes.2018.421573
Mostafa, W., Donia, S., El-gazzar, A. (2018). 'Synthesis of new imidazolone derivatives and evaluated their biological activities', EKB Journal Management System, 5(4), pp. 349-371. doi: 10.21608/jbes.2018.421573
Mostafa, W., Donia, S., El-gazzar, A. Synthesis of new imidazolone derivatives and evaluated their biological activities. EKB Journal Management System, 2018; 5(4): 349-371. doi: 10.21608/jbes.2018.421573

Synthesis of new imidazolone derivatives and evaluated their biological activities

Journal of Basic and Environmental Sciences
Volume 5, Issue 4, October 2018, Page 349-371  XML PDF (1.03 MB)
Document Type: Original Article
DOI: 10.21608/jbes.2018.421573
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Authors
Wesam A. Mostafa; Shafey G. Donia; Amaal Y. El-gazzar
Chemistry Department, Faculty of Science,Benha University
Abstract
Some novel imidazolone derivatives were synthesized in excellent yields and evaluated for their antifungal activities. The structures of the prepared compounds were proved by IR, 1H-NMR, Mass spectra. The antifungal activities of imidazolone derivatives were evaluated by the agar well diffusion method. From the result of biological activity 2-((4-(4-chlorobenzylidene)-5-oxo-4,5-dihydrooxazol-2-yl)methyl)isoindoline-1,3-dione (1) showed high activity against Aspergillus flavus and Aspergillus ochrachous.
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