Optimization by a Response Surface Methodology for Extraction of Essential Oil from Ginger (Zingiber rubens) in Vietnam
Nguyen, T., Le, M., Tran, T., Nguyen, N., Nguyen, V., Mai, C. (2025). Optimization by a Response Surface Methodology for Extraction of Essential Oil from Ginger (Zingiber rubens) in Vietnam. EKB Journal Management System, (), -. doi: 10.21608/ejchem.2025.355642.11214
Thuong Nhan Phu Nguyen; Minh Kha Le; Thanh Tra Thi Tran; Ngoc Lan Thi Nguyen; Viet Nguyen; Cang Huynh Mai. "Optimization by a Response Surface Methodology for Extraction of Essential Oil from Ginger (Zingiber rubens) in Vietnam". EKB Journal Management System, , , 2025, -. doi: 10.21608/ejchem.2025.355642.11214
Nguyen, T., Le, M., Tran, T., Nguyen, N., Nguyen, V., Mai, C. (2025). 'Optimization by a Response Surface Methodology for Extraction of Essential Oil from Ginger (Zingiber rubens) in Vietnam', EKB Journal Management System, (), pp. -. doi: 10.21608/ejchem.2025.355642.11214
Nguyen, T., Le, M., Tran, T., Nguyen, N., Nguyen, V., Mai, C. Optimization by a Response Surface Methodology for Extraction of Essential Oil from Ginger (Zingiber rubens) in Vietnam. EKB Journal Management System, 2025; (): -. doi: 10.21608/ejchem.2025.355642.11214

Optimization by a Response Surface Methodology for Extraction of Essential Oil from Ginger (Zingiber rubens) in Vietnam

Egyptian Journal of Chemistry
Articles in Press, Accepted Manuscript, Available Online from 14 April 2025  XML
Document Type: Original Article
DOI: 10.21608/ejchem.2025.355642.11214
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Authors
Thuong Nhan Phu Nguyen email 1; Minh Kha Le2; Thanh Tra Thi Tran3; Ngoc Lan Thi Nguyen4; Viet Nguyen5; Cang Huynh Maiorcid 6
1Department of Natural Product, Faculty of Chemical Engineering and Food Technology, Nong Lam University, Ho Chi Minh City, Viet Nam
2Department of Natural Products, Faculty of Chemical Engineering and Food Technology, Nong Lam University, Ho Chi Minh City 70000, Viet Nam
3Faculty of Chemical Engineering and Food Technology, Nong Lam University, Ho Chi Minh City, Viet Nam
4Department of Natural Products, Faculty of Chemical Engineering and Food Technology, Nong Lam University of Ho Chi Minh City
5Nong Lam University-Vietnam
6Department of Chemical Technology, Nong Lam University, Ho Chi Minh City
Abstract
Using response surface methodology (RSM), this study sought to improve the hydrodistillation process for extracting Zingiber rubens essential oil. To get the best production of essential oils, tests were carried out utilizing a three-factor central mixture design (CCD) with the following parameters: grinding duration 30 - 50 seconds, material-to-water ratio 1/3 - 1/5 g/ml, and distillation time 240 - 360 minutes. A second-order polynomial regression model, reflecting total extraction efficiency as a function of the key hydro-distillation variables, fit strongly (p<0.05) and had a high coefficient of determination (R2 = 0.9628). The highest extraction efficiency (1.456%) was achieved at 43 seconds, 1/4.3 g/ml, and 316 minutes. The chemical makeup of essential oils was evaluated using gas chromatography-mass spectrometry (GC-MS). The predominant component (concentration > 5.0%) in Zingiber rubens essential oil produced by hydro-distillation was discovered to be 7-epi-Sesquithujene (18.71%), which had a high content. The most common compounds were ?-Sesquiphellandrene (9.92%), Citral (9.88%), ?-Curcumene (9.46%), ?-Bisabolene (5.39%), and Camphene (5.08%).
Keywords
Ginger; Essential Oil; Hydrodistillation; GC-MS; Zingiber rubens
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