Autologous Platelet - Rich Plasma versus Phytoestrogen Gel in Management of Menopausal Women with Stress Urinary Incontinence | ||||
| Evidence Based Women's Health Journal | ||||
| Article 36, Volume 15, Issue 15, January 2025, Page 1-7 PDF (390.17 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ebwhj.2024.314100.1352 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Salah Abd El Aziz Bedir  1; Mohamed Bastawesy2; Medhat Heweidy3; Nareman Elhamamy3
| ||||
| 1Obstetrics and Gynecology Department, Faculty of Medicine, Tanta University, Tanta, Egypt | ||||
| 2Urology Department, Faculty of Medicine, Tanta University, Tanta, Egypt | ||||
| 3Obstetrics and Gynaecology Department, Faculty of Medicine, University of Tanta, Tanta, Egypt. | ||||
| Abstract | ||||
| Objectives: The aim of this study was to conduct a comparison between the efficacy of autologous platelet-rich plasma (PRP) and phytoestrogen vaginal gel in the treatment of stress urinary incontinence (SUI) in postmenopausal women. Patients and Methods: This prospective randomized clinical study was carried out on 40 post- menopausal women with mild to moderate SUI, positive cough leakage test result, absence of infection and no surgery related to SUI. Two equal sets of cases were formed.: Group I (PRP group): injected with platelet-rich plasma (PRP) at the mid-urethral site on the anterior vaginal wall close to external urethral sphincter and group Ⅱ (Phytoestrogen gel group): received phytoestrogen gel as intravaginal gel. Results: International consultation on incontinence questionnaire- short form (ICIQ-SF) and incontinence outcome questionnaire (IOQ) were significantly improved after 6 months compared to baseline and in group I (P <0.05). ICIQ-SF, incontinence impact questionnaire (IIQ-7), IOQ, urinary distress inventory (UDI-6) and Overactive Bladder Symptom Scores (OABSS) were significantly lower after 6 months compared to baseline in group I and II (P <0.001). ICIQ-SF, UDI-6 and IIQ-7 were significantly lower after 6 m in Group I than in Group II (P<0.05). The success rate was significantly higher in group I than in group II (P =0.027). Conclusions: In menopausal women with SUI, the repeated PRP injection was more effective and safer in alleviating SUI than phytoestrogen gel. | ||||
| Keywords | ||||
| Menopausal women; phytoestrogen gel; platelet- rich plasma; stress urinary incontinence | ||||
|
Statistics Article View: 125 PDF Download: 76 |
||||
