Benefits of Systematic Pelvic and Para-Aortic Lymphadenectomy in Advanced Ovarian Epithelial Cancer | ||||
| International Journal of Medical Arts | ||||
| Article 6, Volume 7, Issue 6, June 2025, Page 5775-5780 PDF (1.31 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2025.353794.2108 | ||||
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| Authors | ||||
Sayed Rashad Abd El Bary  ; Eid Rezk El Gammal; Ahmed Youssef Abdulhakeem Abdulkader
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| Department of Surgical Oncology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt. | ||||
| Abstract | ||||
| Background: Advanced ovarian epithelial cancer often requires extensive surgical management to improve patient outcomes. This study evaluates the benefits of systematic pelvic and para-aortic lymphadenectomy in terms of survival rates, operative parameters, and recovery in patients with advanced stages of the disease. Patients and Methods: We performed an observational prospective study in the interval between May 2019 and January 2023. The study was conducted at Al-Azhar University Hospital. We included a total of 50 female patients presenting with pelvi-abdominal swelling. We included two groups; Group one undergoing the conventional de-bulking surgery and the second group was submitted to the same procedures as group A, with the addition of systematic pelvic lymphadenectomy up to the level of the aortic bifurcation. Results: As regards the LNs state, the mean number of the removed LNs was 26 with a range of [18-40]. From these LNs, the mean number of malignant ones was 6 with a range of 0-13 [Table 2]. The mean operative time was 121 minutes with arrange of 92 – 182 in group A versus 190 and a range of 125 – 285 in group B [P =0.001]. The mean hospital stay duration was significantly longer in group B than group A [12 vs 8] [Table 3]. In our study, 28% of the patients in group A, needed blood transfusion versus 80% of the patients in group B [P =0.002] [Table 4]. As regards the recurrence rate, it was 72% of the patient in group A versus 60% of the patients in group [P=0.001]. Conclusion: Systematic pelvic and para-aortic lymphadenectomy in advanced ovarian epithelial cancer significantly enhances survival rates and improves operative and recovery parameters, despite a higher rate of postoperative complications. These findings support the incorporation of lymphadenectomy into standard surgical management for appropriately selected patients. Further research is needed to refine techniques and reduce associated risks. | ||||
| Keywords | ||||
| Ovarian Epithelial Cancer; Systematic Lymphadenectomy; Pelvic Lymphadenectomy, Para-aortic Lymphadenectomy | ||||
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