Role of Splenic 2D-Shear Wave Elastography in Diagnosis of Portal Hypertension in Cirrhotic Patients | ||||
| The Medical Journal of Cairo University | ||||
| Volume 93, Issue 03, March 2025, Page 65-71 PDF (140.1 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2025.422743 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| AHMED RAMADAN MOHAMED, M.D.*; SAHAR S. ABDALLAH EISSA, M.Sc.**; HATEM M.S. EL AZIZI, M.D.** and AMR A. HASSAN, M.D.** | ||||
| The Departments of Endemic Medicine* and Radiodiagnosis**, Faculty of Medicine, Cairo University | ||||
| Abstract | ||||
| Background: Portal hypertension as a result of liver cirrho-sis, which lead to severe clinical symptoms and death. Spleen stiffness measurements (SSM) are a noninvasive, simple tech-nique has a correlation with the hepatic venous pressure gradi-ent (HVPG). Aim of Study: This study aimed to determine whether SSM can predict high-risk varices in patients with liver cirrhosis. Patients and Methods: This is a case control study, which took place between December 2021 and April 2022 at the Kasr Al-Ainy Radiology Department’s ultrasound unit, 22 patients with cirrhotic patients and 24 healthy controls participated. SSM and ultrasound were performed in correlated to endoscop-ic findings of varices. Results: Patients were 17 males and 5 female with mean age (49.8), age was positively weakly linked with high shear wave elastography (SWE) values with a p-value of 0.046. p-values of 0.011 indicated a statistically significant difference between high SWE values and higher grade esophageal varices. Age and SWE of >29 kpa are independent predictors of liver cirrhosis, according to multivariate regression analysis, with p-values of 0.016 and 0.002, respectively, and an OR for SWE of 27.2 (3.3-220.3). Conclusion: SSM By 2D-shear wave elastography is a good method for assessment of liver cirrhosis and associated clinically significant portal hypertension. | ||||
| Keywords | ||||
| Liver cirrhosis; Portal hypertension; Splenic stiffness; SWE | ||||
|
Statistics Article View: 117 PDF Download: 73 |
||||
