CHA2DS2-VASc Score as a Predictor to No-Reflow Phenomenon in Primary Percutaneous Coronary Intervention in ST Segment Elevation Patients
Emam, S., Rasheed, H., EL-Melegy, N., Mashhour, S. (2025). CHA2DS2-VASc Score as a Predictor to No-Reflow Phenomenon in Primary Percutaneous Coronary Intervention in ST Segment Elevation Patients. EKB Journal Management System, (), -. doi: 10.21608/bmfj.2025.327754.2227
Safaa Salah Emam; Hesham Khaled Rasheed; Neama Ali EL-Melegy; Safeya Saleh Mashhour. "CHA2DS2-VASc Score as a Predictor to No-Reflow Phenomenon in Primary Percutaneous Coronary Intervention in ST Segment Elevation Patients". EKB Journal Management System, , , 2025, -. doi: 10.21608/bmfj.2025.327754.2227
Emam, S., Rasheed, H., EL-Melegy, N., Mashhour, S. (2025). 'CHA2DS2-VASc Score as a Predictor to No-Reflow Phenomenon in Primary Percutaneous Coronary Intervention in ST Segment Elevation Patients', EKB Journal Management System, (), pp. -. doi: 10.21608/bmfj.2025.327754.2227
Emam, S., Rasheed, H., EL-Melegy, N., Mashhour, S. CHA2DS2-VASc Score as a Predictor to No-Reflow Phenomenon in Primary Percutaneous Coronary Intervention in ST Segment Elevation Patients. EKB Journal Management System, 2025; (): -. doi: 10.21608/bmfj.2025.327754.2227

CHA2DS2-VASc Score as a Predictor to No-Reflow Phenomenon in Primary Percutaneous Coronary Intervention in ST Segment Elevation Patients

Benha Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 17 April 2025  XML PDF (807.89 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2025.327754.2227
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Authors
Safaa Salah Emam1; Hesham Khaled Rasheed2; Neama Ali EL-Melegy2; Safeya Saleh Mashhour email 3
1Lecturer of cardiovascular medicine Faculty of medicine – Benha University
2Professor of Cardiology, Faculty of Medicine, Benha University
3Cardiology Benha university
Abstract
Background: Primary PCI can be defined as coronary angioplasty/stenting Without prior administration of fibrinolytic agents or GPIIb/IIIa antagonists. This study aimed to evaluate the CHA2DS2-VASc score as a simplified applicable tool to predict the no-reflow among patients with STEMI who will undergo primary PCI. Methods: This Cross-sectional study included 119 patients presenting with ST Segment elevation who underwent primary PCI. Patients were divided into 2 groups according to the incidence of no reflow into 2 groups: Group 1 (with no reflow) (n=13 (10.92%)). Group 2 (without no-reflow) (n=106 (89.08%). Results: CHA2DS2-VASc score can significantly predict the incidence of no reflow with AUC of 0.991, P value of <0.001, at cutoff value >3, with 100% sensitivity, 98.11% specificity, 86.7% PPV and 100% NPV. The univariate logistic regression analysis showed that age 65-74 years, age ≥75, history of stroke, CHA2DS2-VASc score, stent diameter, stent length and diagnosis were the significant predictors of the incidence of no reflow. Conclusion: The study demonstrates a significant association between higher CHA2DS2-VASc scores and the occurrence of the no-reflow phenomenon in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The findings suggest that the CHA2DS2-VASc score, originally developed for predicting thromboembolic events in atrial fibrillation, holds promise as a simplified and applicable tool for identifying individuals at greater risk of microvascular dysfunction.
Keywords
CHA2DS2-VASc Score; No-Reflow Phenomenon; Primary Percutaneous Coronary Intervention; ST Segment Elevation
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