Clinical Outcomes among Patients with Severe Aortic Stenosis Treated with Transcatheter Aortic Valve Implantation: A Single Center Experience | ||
| The Medical Journal of Cairo University | ||
| Volume 93, Issue 03, March 2025 PDF (291.75 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjcu.2025.422996 | ||
| Author | ||
| MAHMOUD BARAKA, M.D.; DIAA KAMAL, M.D.; MOHAMED YEHIA, M.Sc. and AHMAD E. MOSTAFA, M.D. . | ||
| The Department of Cardiology, Faculty of Medicine, Ain Shams University | ||
| Abstract | ||
| Background: Transcatheter aortic valve implantation (TAVI) has become an appealing treatment option in elderly pa-tients with aortic stenosis, especially in patients with increased surgical risk. Aim of Study: To report local expertise, clinical outcomes, and 6-month follow-up of patients undergoing TAVI. Patients and Methods: This study is retrospective and pro-spective, conducted from January 2022 to May 2023. It includ-ed 151 patients treated with TAVI. However, 29 patients were missed during follow-up, to complete the study with 122 pa-tients fulfilling the inclusion criteria. Results: The mean age was 73.67±7.04 years, 52.5% were females, and 59% were low riskaccording to Euro Score II. Three valve platforms were used and Evolut R was the most common (78.6%). Survival rate at 30-days was 97.5%, and 96.7% at 6-months. Incidence of stroke was 1.6% at 1-month, permanent pacemaker implantation 6.6%, no acute kidney in-jury, 2 patients experienced vascular complications (1.6%), and no patients had more than mild paravalvular leakage. Regard-ing symptomatology, there was ahighly significant improve-ment at the 6-month follow-up in which the majority of patients became at NYHA I (91.8%) and II (7.4%) (p<0.001). The Euro quality of life questionnaire was used and revealed significant improvement in general health status in all five dimensions with an overall Euro-quality of life visual analogue scale (EQ-VAS) score of 62.48±4.99 at baseline and 84.92±7.33 at follow-up (p<0.001). Conclusions: Our study demonstrated low rates of proce-dure-related complications, favorable short-term clinical out-comes, and a significant improvement in symptomatology and general health status. | ||
| Keywords | ||
| Aortic stenosis; Transcatheter aortic valve im-plantation; TAVI-registry; Valve Academic Re-search Consortium-3; Self-expandable valves; Balloon-expandable valves | ||
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