Thulium Laser Enucleation of The Prostate for Treatment of Benign Prostatic Hyperplasia: A Single Center Experience

Abdelaziz, Ali Abdelaziz Ali; Selmy, Gamal Ibrahim; Elshal, Ahmed Mohamed; Aboelsaad, Ahmed Yousef

doi:10.21608/ijma.2023.229441.1774

	Thulium Laser Enucleation of The Prostate for Treatment of Benign Prostatic Hyperplasia: A Single Center Experience
International Journal of Medical Arts
Articles in Press, Accepted Manuscript, Available Online from 18 April 2025
Document Type: Original Article
DOI: 10.21608/ijma.2023.229441.1774
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Authors
Ali Abdelaziz Ali Abdelaziz ¹; Gamal Ibrahim Selmy²; Ahmed Mohamed Elshal³; Ahmed Yousef Aboelsaad ¹
¹Department of Urology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt
²Department of Urology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt
³Department of Urology, Faculty of Medicine, Mansoura University, Mansoura, Egypt
Abstract
Background: Benign prostatic hyperplasia (BPH) is a prevalent medical condition in older men that leads to symptoms affecting the lower urinary system (LUTS). Thulium Laser Enucleation of The Prostate (THULEP) seems to be a promising procedure for treatment of BPH with minimal side effects. Objective: To evaluate the outcomes of THULEP in patients with benign prostatic hyperplasia. Patients and methods: A prospective non-controlled study included 30 participants who have failed medical therapy to LUTS attributable to BPH, and underwent THULEP. The primary outcome was International prostate symptom scores (IPSS) score at 6 months. Other outcomes included operative time, intraoperative complications, length of hospital stay, changes in the maximum flow rate, post voiding residual (PVR), prostate-specific antigen (PSA) and continence status. Results: The mean (range) prostate size was 72.3 (40-124) ml, the mean operative duration was 86.40 (48-123) min and the mean enucleation time 73.33 (40-105) min. The improvements in IPSS, Qmax, PVR and PSA were significant (P < 0.001), with mean values before and after THULEP (IPSS from 25 to 2.5, Qmax from 10 ml/sec to 18.1 ml/sec, PVR from 92.5 to 13 ml, PSA from 3 to 1.05, respectively). Of the 30 patients, 20 (66.6%) were catheter-free on the first day after THULEP; the mean hospital stay was 2.63 days. Conclusion: The BPH can be completely removed with ThuLEP. The methods combine high effectiveness with negligible negative effects.
Keywords
Prostate; Prostatic Hyperplasia; Laser Coagulation


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