Protective Effects of Probiotic Bacteria on Experimental Animals Liver Dysfunction | ||
| مجلة البحوث في مجالات التربية النوعية | ||
| Volume 11, Issue 57, March and April 2025, Pages 845-857 PDF (818.09 K) | ||
| Document Type: المقالة الأصلية | ||
| DOI: 10.21608/jedu.2025.354717.2189 | ||
| Authors | ||
| Samar شعوير* 1; ناصر زهران2 | ||
| 1كلية التربية النوعية جامعة الاسكندرية قسم الاقتصاد المنزلي | ||
| 2قسم التغذية - مستشفيات جامعة المنوفية - شبين الكوم - مصر | ||
| Abstract | ||
| The present study was designed to investigate the effects of probiotics on the nutritional status and some biochemical parameters of plasma and liver of carbon tetrachloride-induced hepatotoxicity in male albino rats. Twenty five (25) of Sprague-Dawley white male albino rats, each weighing 200±10 g. The rats were divided into five main groups (5 rats each) as follows: group (1) negative or normal group (-Ve): fed on basal diet only, as a control negative. Group (2) positive group (+Ve): fed on basal diet after injection with CCl4, as a control positive. Treated groups: liver disorders group by CCl4, this groups were furtherly divided into three groups as follow: group (3): fed on basal diet plus 10% of sour milk. Group (4): fed on basal diet plus 10% of yogurt. Group (5): fed on basal diet plus 10% of kishk. The results indicated that CCl4 injection was associated with significant increases in the serum levels of total protein and albumin as well as AST and ALT activity as compared with negative control and other diets. As for the TC, TG, LDL-c and VLDL-c; the results found that the group fed on Kishk 10% showed a high significant differences at (P <0.01) compared to the positive control group. This study showed that using yogurt, sour milk, and kishk can protected CCl4– induced hepatotoxicity. | ||
| Keywords | ||
| Probiotic bacteria; liver dysfunction; rats; milk; sour milk | ||
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