Impact of Some Biochemical Markers in the Development of Early dysfunction for Transplanted Liver
Hussin, M., Elbakry, K., Abdulaziz, M., Abdelwahab, M., Hyder, A., El-Sayed, A. (2025). Impact of Some Biochemical Markers in the Development of Early dysfunction for Transplanted Liver. EKB Journal Management System, 15(1), 41-54. doi: 10.21608/sjdfs.2025.354241.1217
Magda Hussin; Kadry Elbakry; Mohammed Abdulaziz; Mohamed A. Abdelwahab; Ayman Hyder; Amina M. R. El-Sayed. "Impact of Some Biochemical Markers in the Development of Early dysfunction for Transplanted Liver". EKB Journal Management System, 15, 1, 2025, 41-54. doi: 10.21608/sjdfs.2025.354241.1217
Hussin, M., Elbakry, K., Abdulaziz, M., Abdelwahab, M., Hyder, A., El-Sayed, A. (2025). 'Impact of Some Biochemical Markers in the Development of Early dysfunction for Transplanted Liver', EKB Journal Management System, 15(1), pp. 41-54. doi: 10.21608/sjdfs.2025.354241.1217
Hussin, M., Elbakry, K., Abdulaziz, M., Abdelwahab, M., Hyder, A., El-Sayed, A. Impact of Some Biochemical Markers in the Development of Early dysfunction for Transplanted Liver. EKB Journal Management System, 2025; 15(1): 41-54. doi: 10.21608/sjdfs.2025.354241.1217

Impact of Some Biochemical Markers in the Development of Early dysfunction for Transplanted Liver

Scientific Journal for Damietta Faculty of Science
Volume 15, Issue 1, April 2025, Page 41-54  XML PDF (712.82 K)
Document Type: Original articles
DOI: 10.21608/sjdfs.2025.354241.1217
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Authors
Magda Hussin email 1; Kadry Elbakryorcid 2; Mohammed Abdulaziz3; Mohamed A. Abdelwahab4; Ayman Hyderorcid 5; Amina M. R. El-Sayed4
1Department of Zoology, Damietta Faculty of Science, Damietta, Egypt
2Zoology Dep. Faculty of Science, Damietta University
3Gastrointestinal Surgery Center, Mansoura University
4Gastrointestinal Surgery Center, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
5Faculty of Science Damietta University
Abstract
The present study aimed to determine the role of some biochemical markers to predict EAD development after living donor liver transplantation (LDLT). Patients and Methods: One hundred twenty patients under went living donor liver transplantation were subjected. Patients were divided into two groups: Eighty-two non-early allograft dysfunction group (NEAD) and thirty-eight early allograft dysfunction group (EAD). Blood levels of different biological markers were estimated at preoperative day and postoperative from day one to day seven using bio and immunochemical assays. Results: Some of biochemical marker levels on preoperative day and on different postoperative days from day one to day seven were significantly different in EAD than NEAD group (p values ranged from < 0.05 to < 0.0001). Conclusion: Some blood biomarkers on preoperative and postoperative days from day one to day seven were correlated with EAD development and the four current models had a significant prediction potential for EAD in LDLT.
Keywords
allograft dysfunction. Living donor; liver transplantation; Platelets; Gamma-glutamyl transferase – Direct bilirubin; area under curve
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