Effect of Platelet‐Rich Plasma in Treatment of Cervical Ectopy | ||
| Al-Azhar University Journal of Medical and Virus Researches and Studies | ||
| Volume 6, Issue 4, December 2024, Pages 139-147 PDF (366.84 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/aujv.2024.424667 | ||
| Abstract | ||
| Ectopy occurs when the columnar epithelium of the endocervical canal extends outwards into the ectocervix, which is normally covered by stratified squamous epithelium. Platelet-rich plasma (PRP) is an innovative treatment designed to stimulate cellular regeneration, neovascularisation, and healthy cell formation. To study the effectiveness and efficacy of PRP in the treatment of patients with chronic cervicitis. This was a prospective cohort study, was carried out at the gynaecology department of Al-Zahraa University Hospital on 200 females having symptomatic cervical ectopy. Full history taking and examination, PAP smear, colposcopy examination, preparation and application of Platelet-rich plasma (PRP) gel, and follow-up visits with colposcopic assessments. The patient is positioned in a lithotomy position for the examination and PRP application, advised to avoid sexual intercourse and vaginal douching for a month, and the procedure is repeated again after 7 days. The follow-up visits are conducted after 1st, 4th and 12th weeks after treatments. There was high statistically significant difference between cured and non-cured patients as regard presence of irregular vessels during colposcopic examination by green filter (P<0.0001). There was significant positive correlation between contact bleeding, Nabothian cyst, ectopy and endocervical hyperplasia with time of cure (P = 0.023, 0.038, 0.011 and 0.018 respectively). Conclusion: PRP may become the treatment of choice for symptomatic cervical ectopy but long-term evaluations and large randomized controlled trials are needed. | ||
| Keywords | ||
| Adverse effect; Cervical ectopy; Laser treatment; Platelet-rich plasma; Therapeutic effect | ||
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