AN OVERVIEW ON SCRUB TYPHUS (MITE-BORNE TYPHUS): IS IT A NEGLECTED ZOONOSIS DISEASE IN EGYPT? | ||||
Journal of the Egyptian Society of Parasitology | ||||
Article 6, Volume 55, Issue 1, April 2025, Page 37-46 PDF (712.55 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/jesp.2025.424999 | ||||
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Authors | ||||
Tosson A. Morsy1; MOHSEN RAGHEB MOHAMAD2; MAMDOUH M. EL BAHNASAWY3; HAITHAM A. El HADIDY4; MOHAMED BAKR F. ALATTAR5; AMR ALY I. ELSHERIF6 | ||||
1Department of Parasitology, Faculty of Medicine, Ain Shams University, Cairo, 11566, Egypt | ||||
2Department of Gastroenterology, Air Forces General Hospital, Cairo, 11779, Egypt | ||||
3Department of Tropical Medicine and Fever, Military Medical Academy, Cairo, 11291, Egypt | ||||
4Department of Public Health, Military Medical Academy, Cairo, 11291, Egypt | ||||
5Department of Public Health, Military Medical Academy, Cairo, 11291, Egypt | ||||
6Department of Clinical Pathology, Military Medical Academy, Cairo, 11291, Egypt | ||||
Abstract | ||||
Scrub typhus or bush typhus is a mite-borne infectious disease caused by Orientia tsutsugamu- shi (formerly Rickettsia tsutsugamushi), a gram-negative coccobacillus antigenic distinct from trickett sia typhus group. Infection begins insidiously with headache, anorexia, and malaise, or start abruptly with chills, severe headache, myalgias and high fever or pneumonitis, meningoencephalitis, jaundice meningitis and/or meningo-encephalitis or even spontaneous pregnancy risky outcomes. An Escher or dark rash may develop in a subset of patients. Severe complicated infection can range from mild and signs symptoms to multi-organ systemic failure in elderly delayed treated patients. Diagnosis includes serology, biopsy, culture, and PCR. Scrub typhus as anon-specific clinical disease must be differenti ated from other vector-borne diseases as malaria, dengue, chikungunya, other rickettsia diseases, and insect bites as well as leptospirosis and enteric fever as typhoid. | ||||
Keywords | ||||
Chigger bites; Pathogenesis; Diagnosis; Miss-diagnoses; Treatment; Overview | ||||
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