LARVICIDAL AND SYNERGISTIC ACTIVITIES OF LEMON EUCALYPTUS STEM EXTRACTS AGAINST AEDES AEGYPTI | ||
| Journal of the Egyptian Society of Parasitology | ||
| Article 14, Volume 55, Issue 1, April 2025, Pages 117-124 PDF (327.23 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/jesp.2025.425074 | ||
| Authors | ||
| EZE E. AJAEGBU1; CHINYERE J. MBA2; OKONKWO P. CHIKA2; ABDULRASHEED M. BELLO3 | ||
| 1Department of Pharmaceutical and Medicinal Chemistry, David Umahi Federal Uni versity of Health Sciences, Uburu Ebonyi State | ||
| 2Department of Dental Therapy, Federal University of Allied Health Sciences, Trans Ekulu Enugu State | ||
| 3Department of Applied Sciences, Federal University of Allied Health Sciences, Trans Ekulu Enugu State, Nigeria | ||
| Abstract | ||
| Aedes aegypti is the main vector mosquito for transmitting Zika virus, which causes congenital microcephaly and other debilitating conditions. This study assessed the larvicidal and synergistic activities of Lemon eucalyptus stem extracts against the 4th instar larvae of Ae. aegypti. Stem samples were collected, dried, powdered, and extracted using methanol, hexane, ethyl acetate, and acetone. About 64.3% of the extracts caused moderate larvicidal activity after 24 hours. Hexane and acetone extracts showed the highest activity at 1000ppm. The extracts contained saponins, tannins, steroids, flavonoids, alkaloids and resins. Synergistic studies revealed moder ate larvicidal activity for all combinations of extracts at different concentrations. Lemon euca lyptus stem extracts have promising larvicidal and synergistic activities against Ae. aegypti as a safe effective way to stop Zika virus transmission. | ||
| Keywords | ||
| Nigeria; Phytochemical; Aedes aegypti; Zika virus; larvicidal; synergistic | ||
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