Polysaccharide Chemical Functionalization: Innovative Advances, Techniques, Overview and Biological Applications | ||
| Egyptian Journal of Chemistry | ||
| Article 28, Volume 68, Issue 12, December 2025, Pages 339-358 PDF (899.73 K) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2025.368980.11468 | ||
| Authors | ||
| RIMAN M. Alsultan1; Yassine El Ghoul* 2; Chiraz Ammar3 | ||
| 1Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia | ||
| 2Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Qassim, Saudi Arabia | ||
| 3Department of Fashion Design, College of Arts and Design, Qassim University, Buraidah 51452, Saudi Arabia | ||
| Abstract | ||
| Polysaccharides, as renewable and biocompatible biopolymers, have garnered significant attention in materials science and biomedicine. Chemical functionalization particularly through grafting and cross-linking strategies, has emerged as a powerful approach to tailor their chemical, physical, and biological properties for advanced applications. These methods enable precise control over polysaccharide architectures, enhancing mechanical stability, solubility, and bioactivity while preserving their inherent biodegradability and low toxicity. This review highlights recent advancements in polysaccharide modification, emphasizing covalent grafting techniques, including radical polymerization and click chemistry, as well as chemical crosslinking approaches, with a particular focus on their biological applications. | ||
| Keywords | ||
| Grafting; Polymer; Polysaccharides; Functional Polysaccharides; Textile functionalization; biomedical application | ||
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