Assessment of Serum Level of Amyloid A in Patients with Acne Vulgaris | ||
| Benha Medical Journal | ||
| Volume 42, Issue 7, July 2025, Pages 860-867 PDF (540.23 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/bmfj.2025.299060.2111 | ||
| Authors | ||
| Neveen Emad Sorour1; Ahmed Mohamed Hamed2; asmaa adel Elfallah3; Mariam Mohamed AbdElwahed* 4 | ||
| 1Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University | ||
| 2Assistant Professor of Dermatology, Venereology and Andrology, Faculty of Medicine, Benha University | ||
| 3Assistant Professor of Clinical and Chemical Pathology, Faculty of Medicine, Benha University | ||
| 4(M.B.B.Ch, Faculty of Medicine, Cairo University) | ||
| Abstract | ||
| Background: Serum Amyloid A (SAA) is a major acute phase protein produced in large quantity during Acute Phase Reactant (APR). The rise of SAA concentration in blood circulation during APR has been a clinical marker for active inflammation. This study aimed to evaluate serum levels of Amyloid A in patients with acne and its correlation with the disease severity. Methods: This prospective case-control study included 60 patients suffering from acne vulgaris. Patients were divided into 3 equal groups: Group A: patients with mild acne vulgaris. Group B: patients with moderate acne vulgaris. Group C: 20 patients with severe acne vulgaris. In addition, 30 apparently healthy, age and sex matched individuals were included as control group. Results: Serum Amyloid A level was significantly higher in the acne vulgaris group when compared to the control (mean=4.89 versus 1.08, p | ||
| Keywords | ||
| Serum Level; Amyloid A; Disease Severity; Acne Vulgaris | ||
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