The Possible Effect of Bentonite Clay Powder in the Diet for Reducing Pymetrozine -Induced Oxidative Stress, Hepatorenal Dysfunction, and Pathological Alteration in Nile Tilapia | ||||
| Zagazig Veterinary Journal | ||||
| Volume 53, Issue 1, March 2025, Page 23-40 PDF (789.51 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zvjz.2024.328239.1264 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Zainab Albohi; Alshymaa Khalil; Mohamed El-Hady; Fatma Alhady 
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| Department of Aquatic Animal Medicine, Faculty of Veterinary Medicine, Zagazig University, Zagazig 44511, Egypt | ||||
| Abstract | ||||
| This study was aimed to assessing the impact of adding bentonite (BN) clay to the diet as an adsorbent for pymetrozine (PY) in Nile tilapia. Fish were randomly divided into a six triplicate groups. The first group (G1) was exposed to PY at a dose of 0.028 g L-1 (1/10 of 96 h LC50) + basal diet (Bd). The second group (G2) was exposed to PY at a dose of 0.014 g L-1 (1/20 of 96 h LC50) + Bd, whereas the third group (G3) was exposed to PY at a dose of 0.028 g L-1 (1/10 of 96 h LC50) + BN (5 g kg-1 diet). The fourth group (G4) was exposed to PY at a dose of 0.014 g L-1 (1/20 of 96 h LC50) + BN (5 g kg-1 diet), while the fifth group (G5) fed on BN (5 g kg-1 diet). The sixth group (G6) acts as a control group and is fed on a basal diet. There was a 60-day experimental period. In order to compare the examination of several markers and histological alterations, there was a 15-day withdrawal period. The aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), urea, and creatinine, were found to be significantly elevated (p < 0.05) in fish exposed to PY. Serum levels of acetylcholinesterase (AchE), catalase (CAT), copper zinc superoxide dismutase (Cu Zn-SOD), and reduced glutathione (GSH) significantly declined (p < 0.05), whereas the oxidative stress marker malondialdehyde (MDA) significantly enhanced (p < 0.05). The PY-intoxicated fish exhibited the more severe clinical symptoms and postmortem abnormalities. In the BN-treated groups (G3 and G4), the indications' intensity decreased. Notably, adding BN to the food of PY-intoxicated fish can lessen the abnormalities in the majority of the tissue architecture, clinical symptoms, postmortem lesions, and serum biochemical parameters of Nile tilapia. | ||||
| Keywords | ||||
| Pymetrozine; Bentonite; Nile tilapia; Blood-biochemistry; Oxidative stress | ||||
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