EVALUATE THE INFLUENCES OF BUFFALO MILK ON HYPERCHOLESTEROLEMIA AND HYPERLIPIDEMIA IN MALE ALBINO RATS | ||||
Journal of Biological Chemistry and Environmental Sciences | ||||
Volume 14, Issue 1, March 2019, Page 335-353 PDF (509.26 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bces.2019.425755 | ||||
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Abstract | ||||
Hyperlipidemia is a condition of elevated lipid level in blood. Hyperlipidemia is a major cause of atherosclerosis which atherosclerosis related conditions like coronary heart disease (CHD), ischemic cerebrovascular disease, peripheral vascular disease and pancreatitis1-2. The increase in lipids like low density lipoproteins (LDL-c), cholesterol (esters derivatives) and triglycerides are mainly responsible for this condition. This present study was designed to explore the efficiency of the buffalo milk dose in controlling hyperlipidemia . 25 male albino rats were used in this investigation which divided into five groups, The first one was used as a normal health control group (G1), while the remaining four groups were feeding with high-fat diet in order to induce hyperlipidemia. The hyperlipidemic group was divided into hyperlipidemic control group (G2), groups of the treated buffalo milk according to the amount of buffalo milk divided into 1 ml (G 3), 1.5 ml (G 4) and 2 ml (G 5) for 100 g body weight, and the period of the study was for 7 weeks. Blood lipid profile, liver function and kidneys function was measured at the end of the experimental period. This study revealed that there was a significant changes in blood parameters of treated groups in comparison with the other group without any treatment. The buffalo milk group exhibited a significant improvement in lipid profile compared to hyperlipidemic control animals. This study documented the efficiency of the buffalo milk in EVALUATE THE INFLUENCES OF BUFFALO336 controlling of hyperlipidemia and improvement of kidneys function and liver function. So an extensive research on the buffalo milk is still needed to demonstrate this mechanism. | ||||
Keywords | ||||
Key words: Antitoxicants; Buffalomilk; Hypocholesterolemia; Hypolipidemia | ||||
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