Normal Reference Ranges of Uterine and Spiral Arteries Doppler at as Early as 6 Weeks of Gestation and its Significance
Okasha, A., Elmohamady, M., Abdel-Rasheed, M., Hatem, E., Elnahas, T., Salama, E. (2025). Normal Reference Ranges of Uterine and Spiral Arteries Doppler at as Early as 6 Weeks of Gestation and its Significance. EKB Journal Management System, 15(15), 1-5. doi: 10.21608/ebwhj.2024.328521.1371
Ahmed Okasha; Maged Elmohamady; Mazen Abdel-Rasheed; Esraa Hatem; Tamer Elnahas; Ehab Salama. "Normal Reference Ranges of Uterine and Spiral Arteries Doppler at as Early as 6 Weeks of Gestation and its Significance". EKB Journal Management System, 15, 15, 2025, 1-5. doi: 10.21608/ebwhj.2024.328521.1371
Okasha, A., Elmohamady, M., Abdel-Rasheed, M., Hatem, E., Elnahas, T., Salama, E. (2025). 'Normal Reference Ranges of Uterine and Spiral Arteries Doppler at as Early as 6 Weeks of Gestation and its Significance', EKB Journal Management System, 15(15), pp. 1-5. doi: 10.21608/ebwhj.2024.328521.1371
Okasha, A., Elmohamady, M., Abdel-Rasheed, M., Hatem, E., Elnahas, T., Salama, E. Normal Reference Ranges of Uterine and Spiral Arteries Doppler at as Early as 6 Weeks of Gestation and its Significance. EKB Journal Management System, 2025; 15(15): 1-5. doi: 10.21608/ebwhj.2024.328521.1371

Normal Reference Ranges of Uterine and Spiral Arteries Doppler at as Early as 6 Weeks of Gestation and its Significance

Evidence Based Women's Health Journal
Article 45, Volume 15, Issue 15, January 2025, Page 1-5  XML PDF (457.7 K)
Document Type: Original Article
DOI: 10.21608/ebwhj.2024.328521.1371
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Authors
Ahmed Okasha1; Maged Elmohamady2; Mazen Abdel-Rasheed email 3; Esraa Hatem4; Tamer Elnahas1; Ehab Salama1
1Reproductive Health Research Department, National Research Centre, Cairo, Egypt.
2Obstetrics and Gynecology Department, Faculty of Medicine, Cairo University, Cairo, Egypt
3Reproductive Health Research Department, National Research Centre, Cairo, Egypt
4Radiology Department, Bani Suef Health Insurance Hospital, Bani Suef, Egypt.
Abstract
Background: A high uterine artery pulsatility index (PI) reflects a defective development of placental bed spiral arteries. This study assesses early uterine and spiral arteries Doppler and their relation to adverse pregnancy events.
Methods: A retrospective cohort study was conducted on 291 pregnant women between 6 and 10+ weeks’ gestation, where uterine and spiral arteries were assessed by transvaginal Doppler ultrasound at 6-10+ and 11-13+ weeks’ gestation. All participants were followed up regarding the risk for miscarriage, PIH, and the need for neonatal ICU admission.
Results: Normal reference ranges were obtained for mean uterine PI and spiral resistance index (RI) during 6-10+ weeks’ gestation. There was a significantly increased risk of miscarriage in women with higher uterine PI (p=0.042). Besides, there was a moderate positive correlation (r=0.61) between mean uterine PI and spiral RI during the first scan (6 - 10+ weeks). Also, there was a fair, positive correlation (r=0.33) between the mean uterine PI during the first and the second ultrasound scans.
Conclusion: Early measurement of uterine and spiral arteries Doppler may benefit as an early tool for detecting those at risk of miscarriage.
Keywords
Pulsatility index; pregnancy-induced hypertension, resistance index; spiral artery; uterine artery
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