The Potential Effect of Butterfly Pea Flower (Clitoria ternatea L.) Extract on Metabolic Syndrome in rats fed high-fat high-carbohydrate diet | ||||
| مجلة بحوث التربية النوعية | ||||
| Volume 2025, Issue 92, May 2025, Page 401-428 PDF (1020.82 K) | ||||
| Document Type: مقالات علمیة محکمة | ||||
| DOI: 10.21608/mbse.2025.370713.1594 | ||||
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| Authors | ||||
Shaimaa Negm   ; Naglaa Fathy
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| Port Said University | ||||
| Abstract | ||||
| This study evaluated butterfly pea flower extract (BPFE) as a potential nutraceutical manage the complications of Metabolic Syndrome (MetS). The study conducted on 35 male albino rats weighing (170±10g) were divided randomly into two main groups. Group (I) n= (7) fed on a basal diet as the negative control. Group (II) n= (28) were fed a high-fat, high-carb diet (HFCD) before injected by Streptozotocin (STZ) at a dose of 35 mg/kg to create the MetS model. Then divided into four groups (7 rats each), one of them kept as a positive control group, the three left groups were given orally BPFE with doses of 100,200, and 300 mg/kg BW, respectively The study was assigned for 28 day. It was concluded that the extract of the BPF shows had a high content of protein, also antioxidant activity with anthocyanin, tannin and flavonoid content equal to (78.02, 1420.90 mg/100g and 66.78mgQ/g), respectively. Our nutritional and biological results imply that BPFE alleviates metabolic problems by lowering blood glucose levels, lipid profile and atherogenic index, while, enhanced insulin, HDL-c levels, liver enzymes levels. Furthermore, it was successful in restoring the status of oxidative stress (MDA, SOD, CAT, GSH) and inflammatory indicators, such as tumor necrosis factor (TNF-α). Histological examination of liver and pancreas tissue confirmed the results of biochemical analyzes of blood. So that the: It can be recommended that these Butterfly Pea Flower extract could be administered to Metabolic Syndrome when consuming high-fat high-carbohydrate diet. | ||||
| Keywords | ||||
| Clitoria ternatea; Metabolic diseases; Dyslipidemia; Diabetes mellitus; Antioxidant | ||||
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