Antibacterial activity of mentha piperita extraction against uropathogenic bacteria

Al-Malkey, Maysaa Kadhim; Mater, Haifa Nori; Habash, Noor Kadhim

doi:10.21608/mid.2025.375960.2701

	Antibacterial activity of mentha piperita extraction against uropathogenic bacteria
Microbes and Infectious Diseases
Volume 6, Issue 3, August 2025, Page 6134-6140 PDF (667.88 K)
Document Type: Original Article
DOI: 10.21608/mid.2025.375960.2701
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Authors
Maysaa Kadhim Al-Malkey ¹; Haifa Nori Mater ²; Noor Kadhim Habash ³
¹Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad, Iraq
²Department of Biotechnology, College of Science, University of Baghdad, Baghdad, Iraq
³Iraqi Center for Cancer and Medical Genetics Research, Al-Mustansiriyah University, Baghdad, Iraq
Abstract
Background: Urinary tract infections (UTIs) are widespread health issues affecting millions of people annually. Medicinal plants are gaining broad interest as an alternative source of productive and inexpensive bio-remedies to synthetic chemotherapeutic compounds, such as Peppermint. Aim: To evaluate the antibacterial activity of the crude leaf ethanolic peppermint extract against Escherichia coli and Staphylococcus aureus. Methods: The antibacterial activity of Peppermint alcoholic extract at different concentrations was evaluated against uropathogens (Escherichia coli and Staphylococcus aureus). Results: The peppermint extract showed closely sturdy activity towards tested bacterial strains, with inhibition zones showing differences depending on the extract concentration. The inhibition zone diameter in mm was recorded (18.20 ± 0.03) for E. coli and (35.14 ± 0.04) for S. aureus at a (400 mg/ml) concentration. The minimum inhibitory concentration values of the peppermint extract ranged (252 µg/mL and 480 µg/mL) regarding E. coli and S. aureus, respectively. Conclusion: The promising result obtained from the antimicrobial activity has the potential to control several bacterial pathogens.
Keywords
Uropathogens; Mentha piperita; Antibacterial activity


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