PREVALENCE OF VITAMIN D DEFICIENCY IN ADULT EGYPTIAN PATIENTS NEWLY DIAGNOSED WITH ACUTE MYELOID LEUKEMIA AND ITS PROGNOSTIC VALUE
Abdelrahman, A., Nafea, D., Elneily, D., Gerges, B. (2025). PREVALENCE OF VITAMIN D DEFICIENCY IN ADULT EGYPTIAN PATIENTS NEWLY DIAGNOSED WITH ACUTE MYELOID LEUKEMIA AND ITS PROGNOSTIC VALUE. EKB Journal Management System, 7(2), 34-35. doi: 10.21608/alexpo.2025.382734.2162
Ahmed Shehata Abdelrahman; Dalia Ahmed Nafea; Dalia Abd El Moaty Elneily; Bishoy Farid Naguib Gerges. "PREVALENCE OF VITAMIN D DEFICIENCY IN ADULT EGYPTIAN PATIENTS NEWLY DIAGNOSED WITH ACUTE MYELOID LEUKEMIA AND ITS PROGNOSTIC VALUE". EKB Journal Management System, 7, 2, 2025, 34-35. doi: 10.21608/alexpo.2025.382734.2162
Abdelrahman, A., Nafea, D., Elneily, D., Gerges, B. (2025). 'PREVALENCE OF VITAMIN D DEFICIENCY IN ADULT EGYPTIAN PATIENTS NEWLY DIAGNOSED WITH ACUTE MYELOID LEUKEMIA AND ITS PROGNOSTIC VALUE', EKB Journal Management System, 7(2), pp. 34-35. doi: 10.21608/alexpo.2025.382734.2162
Abdelrahman, A., Nafea, D., Elneily, D., Gerges, B. PREVALENCE OF VITAMIN D DEFICIENCY IN ADULT EGYPTIAN PATIENTS NEWLY DIAGNOSED WITH ACUTE MYELOID LEUKEMIA AND ITS PROGNOSTIC VALUE. EKB Journal Management System, 2025; 7(2): 34-35. doi: 10.21608/alexpo.2025.382734.2162

PREVALENCE OF VITAMIN D DEFICIENCY IN ADULT EGYPTIAN PATIENTS NEWLY DIAGNOSED WITH ACUTE MYELOID LEUKEMIA AND ITS PROGNOSTIC VALUE

ALEXMED ePosters
Article 1, Volume 7, Issue 2, April 2025, Page 34-35  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2025.382734.2162
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Authors
Ahmed Shehata Abdelrahman1; Dalia Ahmed Nafea2; Dalia Abd El Moaty Elneily3; Bishoy Farid Naguib Gerges email 4
1Departments of internal medicine, Hematology, Faculty of Medicine, University of Alexandria, Egypt
2Hematology Unit, Department of Internal Medicine, Faculty of Medicine, Alexandria University
3Department of Clinical and Chemical Pathology Faculty of Medicine, University of Alexandria
4Department of Internal Medicine, Faculty of Medicine, Alexandria University.
Abstract
Acute myeloid leukemia (AML) is a malignancy characterized by infiltration of the bone marrow, blood, and other tissues by proliferative, abnormally differentiated, clonal hematopoietic malignant cells.
Vitamin D is a steroid hormone, which is mostly synthesized in the skin following ultraviolet B (UVB) sunlight exposure and to a lesser extent from the diet. Vitamin D plays a central role in maintaining serum calcium and skeletal homeostasis as well as multiple other cellular effects including regulation of differentiation, proliferation, apoptosis, metastatic potential, and angiogenesis.
Vitamin D deficiency was defined as a 25(OH)D level of less than 20 ng/ml (seriously deficient). A level of 21-30 ng/ml was considered to indicate a relative insufficiency and a level of 30 ng/ml or more was considered to indicate sufficient vitamin D (adequately supplied).
Observational studies have indicated that inadequate 25(OH)D levels are a risk factor for certain types of cancer. Far less is known about the relationship between vitamin D and the risk of hematologic malignancy.
AIM:
The aim of this study was to evaluate the prevalence of vitamin D deficiency in adult Egyptian patients newly diagnosed with acute myeloid leukemia (AML) and its correlation with disease status and prognostic markers.
Keywords
AML; Vitamin D; Hematology Unit
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