ROLE OF MORPHOLOGICAL CHANGES BY ULTRASONOGRAPHY IN PREDICTION OF BREAST CANCER MOLECULAR SUBTYPES

Mohallel, Ahmed; Farid El Deeb, Nevine Mohamed; Hassan, Hebatallah H.M.; Ibrahim Ragheb, Sally Mohamed

doi:10.21608/alexpo.2025.382719.2161

	ROLE OF MORPHOLOGICAL CHANGES BY ULTRASONOGRAPHY IN PREDICTION OF BREAST CANCER MOLECULAR SUBTYPES
ALEXMED ePosters
Article 1, Volume 7, Issue 2, April 2025, Page 39-40
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2025.382719.2161
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Authors
Ahmed Mohallel¹; Nevine Mohamed Farid El Deeb²; Hebatallah H.M. Hassan³; Sally Mohamed Ibrahim Ragheb ¹
¹Department of Radiodiagnosis and Intervention, Faculty of Medicine, Alexandria University
²Depatment of Pathology, Faculty of Medicine, Alexandria University
³Radiodiagnosis, Faculty of Medicine , Alexandria University , Alexandria , Egypt
Abstract
1. Introduction Breast cancer is the most common cancer in women. It is a complex disease. The molecular subtyping of breast cancer has emerged as a vital component of breast cancer management recently, and it is now essential for prognosis and therapeutic planning. According to the St Gallen conference (2011) four molecular subtypes can be defined by using the following biomarkers: ER, PR, HER2 and Ki-67. The 4 subtypes are: Luminal A, luminal B, HER2-enriched, and triple negative breast cancer. Breast imaging may have a role in predicting the molecular subtypes of breast cancer. Mammography and ultrasonography are the primary imaging modalities. Ultrasound is known for its high sensitivity and specificity with being non invasive. Consequently, we are attempting to correlate between the molecular subtypes and morphological changes detected on ultrasound such as shape, margins, orientation, surrounding desmoplastic reaction, related parenchymal architecture distortion, calcifications and vascularity. 2. Aim The aim of this study is to evaluate the role of morphological changes detected on ultrasonography in prediction of breast cancer molecular subtypes.
Keywords
ULTRASONOGRAPHY; BREAST CANCER; MOLECULAR SUBTYPES
Supplementary Files 2161 Sally Mohamed Ibrahim Ragheb.pdf

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