Diabetic Population (Type 1 Versus Type 2) Characteristics and Severity of Coronary Artery Disease in Chronic Coronary Syndrome

Adel, Abdelrahman Ahmed; Mousa, Ahmed Shaker; Abdulrahman Mi, Fatma Mohammed; Moustafa, Tamer Mohamed

doi:10.21608/zumj.2025.374422.3902

	Diabetic Population (Type 1 Versus Type 2) Characteristics and Severity of Coronary Artery Disease in Chronic Coronary Syndrome
Zagazig University Medical Journal
Article 18, Volume 31, Issue 6, June 2025, Page 2378-2388 PDF (681.33 K)
Document Type: Original Article
DOI: 10.21608/zumj.2025.374422.3902
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Authors
Abdelrahman Ahmed Adel ¹; Ahmed Shaker Mousa²; Fatma Mohammed Abdulrahman Mi ³; Tamer Mohamed Moustafa⁴
¹Lecturer of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt
²Assistant Professor of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt
³Department of Cardiology, Faculty of Medicine, Sebha University-Libya
⁴Professor of Cardiology Department, Faculty of Medicine, Zagazig university, Egypt
Abstract
Background: Heart disease is the primary cause of death for diabetics. Obesity, systemic hypertension, and hyperlipidemia factors frequently found in diabetic patients have been connected to an increased risk of coronary artery disease (CAD). In order to improve care and lower CAD in diabetic individuals with chronic coronary syndrome (CCS), this study aims to quantify the severity of CAD. Methods: out of 140 diabetic patients with chronic coronary syndrome,70 being type 1diabetes mellitus (T1DM) and 70 are type 2 diabetes mellitus (T2DM), undergone percutaneous coronary angiography (PCI) to evaluate the severity of coronary artery by using syntax and Gensini scores. Results: type 2 diabetes mellitus (DM) were older, 82.9% were males (p<0.001), had higher systolic (150±19.3vs 131.8±14.8) p<0.001 and diastolic (86.4 ± vs 82.1 ± 7.14) p=0.003 blood pressure compared to type 1 DM also, T2DM had higher levels of triglycerides (99.2±27vs 87.1±14.9) p=0.003, higher lower density lipoprotein (LDL) (172.1±32.3vs 158.2±21.7) p=0.001, and poor glycemic control (34.3%vs 11.4%) p=0.002 compared to T1DM Type 2 diabetes mellitus revealed higher Syntax (p<0.001) and Gensini (p<0.001) scores in comparison to type 1 diabetes mellitus. Conclusion: Type 2 diabetes mellitus patients had more sever and a complex coronary artery disease than those with type1 diabetes mellitus.
Keywords
Cardiac disease; Artery Disease; Coronary Syndrome


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