Herbal Phytoconstitutes: Natural Weapon Against Lung Cancer | ||
| Egyptian Journal of Chemistry | ||
| Volume 68, Issue 13, December 2025, Pages 255-288 PDF (962.03 K) | ||
| Document Type: Review Articles | ||
| DOI: 10.21608/ejchem.2025.365750.11408 | ||
| Authors | ||
| hadeel sanad* 1; kamel mahmoud kamel2; Amira kamal El motayam3; mouchira Aly shoukry4; Seham Salah Eldin El Hawary5 | ||
| 1department of pharmacognosy, faculty of pharmacy, Cairo university. | ||
| 2department of pharmacognosy, faculty of pharmacy, MUST university, cairo | ||
| 3Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Kasr El-Ainy Street | ||
| 4pharmacognosy Department, faculty of pharmacy, Cairo university | ||
| 5Pharmacognosy Department, Faculty of Pharmacy, Cairo University | ||
| Abstract | ||
| By the twenty-first century, lung cancer has become well-known as one of the most frequent cancers. Nowadays, Lung cancer ranks second globally regarding new cases and first globally regarding cancer-related deaths. To fight this spreading; surgical procedures, radiation treatment, chemotherapy or combination of these strategies is commonly used. Thanks to their phytochemical compounds; Many plants have proved their efficacy as anticancer agents by different mechanisms as Allium sativum, Curcuma longa, Camellia sinensis and Panax ginseng etc. by Apoptosis, cell cycle arrest, Tyrosine Kinase inhibitors, PI3K/AKT/mTOR inhibitor pathway and Autophagy. In this review article, the effect of using natural plants as anticancer agents and the possibility to use natural plants extracts in combination with chemotherapy to reduce chemotherapy side effects, or to enhance the anticancer activity of chemotherapy, will be examined. | ||
| Keywords | ||
| lung cancer; natural plants; anticancer agents; phytochemical compounds | ||
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