Biosynthesis of Propolis-silver nanoparticles: Optimization and In Vitro Validation for antimicrobial applications | ||
| Mansoura Journal of Chemistry | ||
| Article 1, Volume 68, Issue 2, May 2025, Pages 15-20 PDF (836.49 K) | ||
| Document Type: Original Article | ||
| DOI: 10.21608/mjcc.2025.378536.1005 | ||
| Authors | ||
| Nada Ragab* 1; Omali Elkhawaga2; Emad Tolba3; Manar Refaat4 | ||
| 1Chemistry department Mansoura University | ||
| 2Chemistry, fuculty of science Mansoura University | ||
| 3Polymers and Pigments Department National Research center | ||
| 4Chemistry department fuculty of science Mansoura University | ||
| Abstract | ||
| There is a current research focus on producing bioactive nanomaterials through eco-friendly approaches because of the wide range of uses for these materials in different industries. In this study, a simple and environmentally conscious chemistry approach was utilized to produce silver nanoparticles (AgNPs) using Egyptian propolis as the reducing and capping agent. The resulting silver nanoparticles were characterized using several methods, including UV spectroscopy and TEM. The dimensions of the synthesized silver nanoparticles measured 4.5 ± 1 nm, increasing to 11 ± 4 nm with higher concentrations of silver nitrate. The antimicrobial properties of PP samples, enhanced by varying concentrations of Ag-NPs, effectively inhibit Escherichia coli, Streptococcus mutans, and Candida albicans. Moreover, high MIC values were observed among all samples against Escherichia coli. The antimicrobial activity increases with the increase of Ag-NPs concentration in the PP extracts. These results demonstrate the potential of the Ag-PP sample as an effective antimicrobial agent to combat against bacterial infection. | ||
| Keywords | ||
| silver nanoparticles; propolis; antimicrobial activity; biomedical application | ||
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