Correlation between Physical Function, Health Related Quality of Life and Disease Activity in Juvenile Idiopathic Arthritis Patients Attending Suez Canal University Hospital
El Nagar, T., Nasef, S., El Shahaly, M., El Ashry, K., Omar, A. (2024). Correlation between Physical Function, Health Related Quality of Life and Disease Activity in Juvenile Idiopathic Arthritis Patients Attending Suez Canal University Hospital. EKB Journal Management System, 27(9), 41-49. doi: 10.21608/scumj.2024.428154
Tasneem El Desouky El Nagar; Samah I. Nasef; Mohsen H. El Shahaly; Kareem Mohamed El Ashry; Aziza S. Omar. "Correlation between Physical Function, Health Related Quality of Life and Disease Activity in Juvenile Idiopathic Arthritis Patients Attending Suez Canal University Hospital". EKB Journal Management System, 27, 9, 2024, 41-49. doi: 10.21608/scumj.2024.428154
El Nagar, T., Nasef, S., El Shahaly, M., El Ashry, K., Omar, A. (2024). 'Correlation between Physical Function, Health Related Quality of Life and Disease Activity in Juvenile Idiopathic Arthritis Patients Attending Suez Canal University Hospital', EKB Journal Management System, 27(9), pp. 41-49. doi: 10.21608/scumj.2024.428154
El Nagar, T., Nasef, S., El Shahaly, M., El Ashry, K., Omar, A. Correlation between Physical Function, Health Related Quality of Life and Disease Activity in Juvenile Idiopathic Arthritis Patients Attending Suez Canal University Hospital. EKB Journal Management System, 2024; 27(9): 41-49. doi: 10.21608/scumj.2024.428154

Correlation between Physical Function, Health Related Quality of Life and Disease Activity in Juvenile Idiopathic Arthritis Patients Attending Suez Canal University Hospital

Suez Canal University Medical Journal
Article 5, Volume 27, Issue 9, September 2024, Pages 41-49    PDF (290.36 K)
Document Type: Original Article
DOI: 10.21608/scumj.2024.428154
Authors
Tasneem El Desouky El Nagar* 1; Samah I. Nasef1; Mohsen H. El Shahaly1; Kareem Mohamed El Ashry2; Aziza S. Omar1
1Department of Physical Medicine, Rheumatology and Rehabilitation - Faculty of Medicine - Suez Canal University - Ismailia - Egypt
2Department of Diagnostic and Interventional Radiology, Faculty of medicine, Suez Canal University,Ismailia, Egypt
Abstract
Background: Juvenile idiopathic arthritis (JIA) is the most common inflammatory autoimmune rheumatic disease in children. It leads to impairments in physical function and health related quality of life. Functional ability and good physical function are important elements in evaluation of treatment efficacy and disease control. Objectives: To evaluate the correlation between physical function and health related quality of life with disease activity in juvenile idiopathic arthritis. Methods: Thirty-four children diagnosed with JIA based on the International League Against Rheumatism (ILAR) Criteria. They had a clinical and laboratory assessment as well as an evaluation of their disease activity using the juvenile arthritis disease activity score (JADAS 27 ESR), in addition to the Juvenile Arthritis Multidimensional Assessment Report (JAMAR) for functional evaluation and health-related quality of life (HRQoL). Results: A significant moderate correlation (P value < 0.05) was seen between JADAS 27 ESR and both physical function and HRQoL. All patients with low disease activity had impaired physical function and HRQoL. There was a moderate correlation between active joint count and HRQoL and physical function in JIA patients (r = 0.43, r = 0.65 respectively). Physical function and HRQoL were moderately correlated with ESR (r = 0.44, r = 0.4 respectively). There was a negative correlation between Hemoglobin (Hb) and HRQoL, (r = -0.37, p value=0.02). Conclusion: The study's findings emphasize the significance of measuring HRQoL and physical function as a significant part of clinical evaluation of JIA patients.
Keywords
Juvenile idiopathic arthritis; Physical function; Health related quality of life
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