The Correlation Between Calprotectin Levels And Different Dermatological Diseases
Mohamed, N., Mahmoud, R., Ahmed, O., Mokhtar, A. (2025). The Correlation Between Calprotectin Levels And Different Dermatological Diseases. EKB Journal Management System, 15(1), 68-77. doi: 10.21608/fumj.2025.320901.1392
Noha Ezzat Mohamed; Rania Hosny Mahmoud; Omnia Ehab Ahmed; Asmaa Mohamed Mokhtar. "The Correlation Between Calprotectin Levels And Different Dermatological Diseases". EKB Journal Management System, 15, 1, 2025, 68-77. doi: 10.21608/fumj.2025.320901.1392
Mohamed, N., Mahmoud, R., Ahmed, O., Mokhtar, A. (2025). 'The Correlation Between Calprotectin Levels And Different Dermatological Diseases', EKB Journal Management System, 15(1), pp. 68-77. doi: 10.21608/fumj.2025.320901.1392
Mohamed, N., Mahmoud, R., Ahmed, O., Mokhtar, A. The Correlation Between Calprotectin Levels And Different Dermatological Diseases. EKB Journal Management System, 2025; 15(1): 68-77. doi: 10.21608/fumj.2025.320901.1392

The Correlation Between Calprotectin Levels And Different Dermatological Diseases

Fayoum University Medical Journal
Volume 15, Issue 1, April 2025, Page 68-77  XML PDF (624.2 K)
Document Type: Full Length research Papers
DOI: 10.21608/fumj.2025.320901.1392
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Authors
Noha Ezzat Mohamed1; Rania Hosny Mahmoud2; Omnia Ehab Ahmed email 3; Asmaa Mohamed Mokhtar4
1Dermatology, venerology and STDs department, Faculty of medicine, Fayoum University, fayoum, Egypt
2Medical Biochemistry and Molecular Biology, Faculty of Medicine, Fayoum University, Fayoum, Egypt
3Dermatology, venerology and STDs department, faculty of medicine, fayoum university. fayoum, Egypt
4Dermatology, venerology and STDs department. Faculty of medicine, Fayoum University, fayoum, Egypt
Abstract
Abstract
Introduction: Calprotectin plays a crucial role in the body's inflammatory response. It serves as a biomarker for inflammation and autoimmune conditions, including dermatological diseases.
Aim of the study: To assess the relation between Calprotectin levels and the development of different dermatological diseases.
Subjects and Methods: We searched Cochrane, Web of Science, PubMed, and SCOPUS for relevant articles. We utilized a strategy for our search by combining these keywords: (‘’ Calprotectin ’’) AND (‘’ psoriasis ‘’ OR ‘’ systematic Lupus Erythematosus ‘’ OR ‘’ Alopecia Areata ‘’ OR ‘’ dermatological diseases ‘’). Quality evaluation of the involved studies was assessed regarding to Cochrane’s risk of bias tool.
Results: we found that the levels calprotectin affected by different skin diseases as individuals suffering from systematic lupus erythematosus, atopic dermatitis, and psoriasis showed substantially higher levels of Calprotectin than healthy participants.
Conclusions: Calprotectin has major role in pathogenesis of several skin diseases. Also, it has a diagnostic and therapeutic value in many skin diseases.
Keywords
Calprotectin; alopecia areata; psoriasis; atopic dermatitis
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